902 Harga
533 Catatan reproduksi
700 Entri Tambahan Nama Orang
336 Content Typeteks (rdacontent)
264b Nama PenerbitOfficial publicaation of the SEAMEO regional tropical medicine and public health network (TROPMED)
710 Entri Tambahan Badan Korporasi
091 No. Panggil Setempat Majalah610 TSAJ 40:4 (2009)
049 No. Barkod
852 LokasiPerpustakaan UI, Lantai 4, R. Koleksi Jurnal
515 Penyimpangan/penomoran
338 Carrier Typevolume (rdacarier)
490 Seri
270 Alamat Penerbit, SuplierFaculty of Tropical Medicine, Mahidol University 420/6 Ratchawithi Road, Bangkok 10400, Thailand.
590 Cat. Sumber Pengadaan Koleksi
053 No. Induk
321 Frekuensi lama
653 Kata KunciFalciparium; public health; southeast asean
040 Sumber PengataloganLibUI eng rda
245 Judul UtamaThe southeast asian journal of tropical medicine and public health
264c Tahun Terbit
650 Subyek TopikMedicine & health
850 Lembaga PemilikUniversitas Indonesia
904b Pemeriksa Lembar KerjaFakhriMubin
520 Ringkasan/Abstrak/IntisariThis study aimed to demonstrate class switch recombination (CSR) in heavy chain expressing immunoglobulin G (IgG) and IgE in human B cells (CD20+CD27-) were cultured with crude P. falciparum antigen (cPfAg) and anti-CD40. on day 4 post-exposure, total RNA from B cells was prepared and the occurance of CSR from IgM to IgG and/or IgE was investigated by reverse transciption-polymerase chain reaction. Molecular markers to detect active CSR included enzyme activation-induced cytidine deaminase mRNA, y and e-germline transcripts (y,e-GLT), circle transcript (CT) and mature transcript (y and e-mRNA) expression. On day 7 and day 14 after exposure, levels of Igs in the culture supernatant were determined by enzyme-linked immunosorbent assay. Our findings showed that we could demonstrate cPfAg-stimulated B cells undergoing CSR by use of the expressed CSR markers and the increase in spesific IgG and IgE indicating the potential of this approach in the study of CSR in P. falciparum stimulated B cells.
022 ISSN (R)01251562
525 Cat. suplemen/index/spec. issua
090 No. Panggil Setempat610 TSAJ
061 Tanggal akhir diterima/langgan
500 Catatan Umum
337 Media Typeunmediated (rdamedia)
100 Entri Utama Nama Orang
264a Kota TerbitBangkok, Thailand
300 Deskripsi Fisik
904a Pengisi Lembar Kerja
856 Akses dan Lokasi Elektronik
246 Judul Alternatif
310 Frekuensi Terbit
041 Kode Bahasaeng
362 Tanggal Terbit Awal