902 Harga;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;
533 Catatan reproduksi
700 Entri Tambahan Nama Orang
336 Content Typetext (rdacontent)
264b Nama PenerbitDepartment of Pharmaceutical Chemistry The University of Kansas
710 Entri Tambahan Badan Korporasi
091 No. Panggil Setempat Majalah615 JPS 86:12 (1997);615 JPS 90:8 (2001);615 JPS 90:1 (2001);615 JPS 86:5 (1997);615 JPS 90:2 (2001);615 JPS 90:3 (2001);615 JPS 90:4 (2001);615 JPS 90:9 (2001);615 JPS 90:10 (2001);615 JPS 90:6 (2001);615 JPS 90:12 (2001);615 JPS 90:5 (2001);615 JPS 86:1 (1997);615 JPS 85:10 (1996);615 JPS 86:4 (1997);615 JPS 86:11 (1997);615 JPS 85:4 (1996);615 JPS 86:10 (1997);615 JPS 85:5 (1996);615 JPS 85:1 (1996);615 JPS 86:6 (1997);615 JPS 85:8 (1996);615 JPS 85:12 (1996);615 JPS 86:3 (1997);615 JPS 85:6 (1996);615 JPS 85:2 (1996);615 JPS 85:11 (1996);615 JPS 86:8 (1997);615 JPS 85:9 (1996);615 JPS 86:7 (1997);615 JPS 85:3 (1996);615 JPS 85:7 (1996);615 JPS 86:9 (1997);615 JPS 86:2 (1997)
049 No. Barkod04-18-047260595;04-19-028294206;04-18-361728390;04-18-805875586;04-18-326838117;04-18-083421333;04-18-477701619;04-18-483219748;04-18-950821868;04-18-797906467;04-18-965486199;04-18-190556460;04-18-084619420;04-18-974143201;04-18-006025012;04-18-209241839;04-18-198302131;04-18-782171055;04-18-669308280;04-18-743659091;04-18-658221059;04-18-201063314;04-18-113153663;04-18-568762320;04-18-268888897;04-18-090038201;04-18-385209758;04-18-487083420;04-18-597421899;04-18-365437567;04-18-497752409;04-18-876695780;04-18-805333278;04-18-915513482
852 LokasiPerpustakaan UI, Lantai 4, R. Koleksi Jurnal
515 Penyimpangan/penomoran
338 Carrier Typevolume (rdacarrier)
490 Seri
270 Alamat Penerbit, SuplierThe University of Kansas
590 Cat. Sumber Pengadaan KoleksiPenerbit;;;Penerbit;;;;;;;;;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit;Penerbit
053 No. Induk04-18-047260595;04-19-028294206;04-18-361728390;04-18-805875586;04-18-083421333;04-18-477701619;04-18-483219748;04-18-950821868;04-18-797906467;04-18-965486199;04-18-190556460;04-18-084619420;04-18-974143201;04-18-326838117;04-18-006025012;04-18-209241839;04-18-198302131;04-18-782171055;04-18-669308280;04-18-743659091;04-18-658221059;04-18-201063314;04-18-113153663;04-18-113153663;04-18-268888897;04-18-090038201;04-18-385209758;04-18-487083420;04-18-597421899;04-18-365437567;04-18-497752409;04-18-876695780;04-18-805333278;04-18-915513482
321 Frekuensi lama
653 Kata Kuncipharmacology; medicine; health
040 Sumber PengataloganLibUI eng rda
245 Judul UtamaJournal of pharmaceutical sciences
264c Tahun Terbit2018
650 Subyek TopikPharmacology
850 Lembaga PemilikUniversitas Indonesia
904b Pemeriksa Lembar KerjaWinarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;Winarsih;
520 Ringkasan/Abstrak/IntisariABSTRAK
Delivery of pharmacological doses of proteins to people has raised concerns of inducing immune responses, especially when the protein is provided in multiple doses over an extended period of time. Immune responses could impact the therapeutic exposure and efficacy of the protein itself. In addition, there have been fears of anaphylaxis or autoimmunity. This review summarizes the available literature regarding the measurement and evaluation of immune responses observed during clinical assessment of recombinant human proteins. Immune responses have ranged from none at all to inactivation and/or accelerated clearance. Presence of antibodies does not necessarily impact therapeutic viability. While responses are related to frequency and route of delivery, there is no clear relationship that enables one to predict the clinical experience.
022 ISSN (R)00223549
525 Cat. suplemen/index/spec. issua
090 No. Panggil Setempat615 JPS
061 Tanggal akhir diterima/langgan
500 Catatan Umum
337 Media Typeunmediated (rdamedia)
100 Entri Utama Nama Orang
264a Kota TerbitWashington DC
300 Deskripsi Fisik
904a Pengisi Lembar KerjaDewi Yulianti;Jovita Ayuningtyas;Dewi Yulianti;Jovita Ayuningtyas;Jovita Ayuningtyas;Jovita Ayuningtyas;Jovita Ayuningtyas;Alyssa-Maret19;Alyssa-Maret19;Alyssa-Maret19;Alyssa-Maret19;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Dewi Yulianti;Alyssa-Maret19
856 Akses dan Lokasi Elektronik
246 Judul Alternatif
310 Frekuensi TerbitBulanan
041 Kode Bahasaeng
362 Tanggal Terbit Awal