Exhalation Channel Infection Disease of Acute (ISPA) be one of health problem of main public because still height of mortality because ISPA espicially at baby and balita. In Sub-Province Bandung death because ISPA reachs 54,55% and in kecamatan Gununghalu x'self patient ISPA at balita experiences improvement from the year 2003 until the year 2005. Risk the increasing of ISPA can be influenced by low economic social status , condition of housing which still varying according to quality of its (the building, causing is required research about factor relating to case of ISPA at balita. This researh type is analytic observasional with planning cross sectional. Variable which is accurate is house wall type, house floor type, ventilation wide of house, situation of house temperature, house dampness, existence of hole smoke of kitchen, unmate density, ripe fuel type, usage of anti mosquito drug, smoking habit member of family, umminization status, status gizi, time body weight borned and case of ISPA at balita. Result of research with test chi square there is relationship having a meaning (of) between house wall types (p value = 0,044 and OR = 3, 338), ventilation wide of house (p value = 0,030 and OR = 3,589), house temperature (p value = 0.023 and OR = 2,972) existence of hole smoke of kitchen (p value = 0,014 and OR = 3,824) smoking habit member of family (p value = 0,022 and OR = 6,182) status gizi (p value = 0,000 and OR = 12,600) and time body weight borned (p value = 0,049 and OR = 5, 800) dengan case of ISPA at balita. suggestion is given by intensifying counselling to public about healthy house and preventive effort the happening of ISPA at balita.