Kepatuhan pasien dalam melakukan pengobatan merupakan salah satu faktor yang menentukan dalam keberhasilan terapi, namun kepatuhan untuk melakukan pengobatan oleh pasien sering kali rendah, termasuk pada pengobatan tuberkulosis (TB) paru. Penelitian bertujuan untuk mengevaluasi kepatuhan berobat penderita tuberkulosis paru di Puskesmas Kecamatan Pancoran Mas Depok. Desain penelitian menggunakan studi potong lintang dengan 76 responden. Pengambilan data melalui wawancara langsung menggunakan kuesioner dengan metode consecutive sampling. Sampel adalah penderita TB paru berusia minimal 15 tahun yang telah minum obat minimal selama 2 bulan dan datang berobat pada bulan Februari-April 2011. Hasil penelitian menunjukkan bahwa terdapat 43% responden yang patuh terhadap pengobatan tuberkulosis paru. Ada hubungan antara jarak dan peran keluarga/ pengawas menelan obat (PMO) dengan kepatuhan berobat penderita TB paru, tetapi tidak ada hubungan antara factor sosiodemografis (jenis kelamin, usia, pendidikan, pekerjaan, jumlah pendapatan keluarga per bulan), pengetahuan, efek samping obat, riwayat penyakit lain, ketersediaan transportasi dan peran petugas tuberkulosis di puskesmas dengan kepatuhan berobat penderita tuberkulosis paru di Puskesmas Kecamatan Pancoran Mas Depok. Studi menunjukkan tingginya angka ketidakpatuhan berobat pada penderita tuberkulosis paru. Oleh karena itu, peran keluarga/ PMO dalam mengawasi pengobatan perlu ditingkatkan sehingga penyebaran penyakit dan meluasnya resistensi bakteri dapat dicegah.

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Compliance of patients in making treatment is one factor that determines the success of therapy, but adherence to treatment by patients is often low, including in the treatment of tuberculosis (TB). The study aims to evaluate treatment compliance of patients with pulmonary tuberculosis in Pancoran Mas Depok District Health Center. Design research using cross sectional study with 76 respondents. Retrieval of data through direct interviews using a questionnaire with a consecutive sampling method. Samples were pulmonary TB patients at least 15 years old who had been taking medication for at least two months and come for treatment in February-April 2011. The results showed that there were 43% of respondents who adhere to the treatment of pulmonary tuberculosis. There is a relationship between the distance and family's role/ supervisor-medication (PMO) with pulmonary TB patient treatment compliance, but there is no relationship between sosiodemografis factors (sex, age, education, occupation, total family income per month), knowledge, drug side effects, history of other diseases, avaibility of transport, and the role of the tuberculosis officer at the health center with pulmonary TB patient treatment compliance in Pancoran Mas Depok District Health Center. Studies show high rates of medication adherence in patients with pulmonary tuberculosis. Therefore, the role of family / PMO in monitoring the treatment needs to be improved so that the spread of disease and spread of bacterial resistance can be prevented.