Human trafficking as a form of contemporary slavery evidently is not fractured by ages, and in fact, it continues to take place in various operation modes. Based on various information sources from the print as well as electronics media and supported by the research data, this phenomenon evidently is increasing all over the world, including Indonesia and often caused casualties especially towards women and children. This research was based from the concern towards the law enforcement on the case of human trafficking in Indonesia, and accordingly emerges the identification of the problems that cover the followings: the condition of women and children human trafficking in Indonesia, regulating this action as an action that is prohibited based on various applicable regulations in Indonesia, the aspect of law enforcement, including the prospect of Draft on Elimination of Human Trafficking which at the current moment is in the process of legalization. To answer these problems, the writer used the bibliography law research method, which is supported by material books and secondary data that is analyzed using the qualitative method and presented in analytical descriptive. From the research, it is discovered that women and children trafficking cases that are currently occurring in Indonesia are intended to obtain economic and sexual exploitation. Further, it is also found that there are various instruments of law and human rights, both national and international, which have classified this action as an act that is prohibited and resulting in a criminal punishment, and besides, the current Draft has also been structured adequately from the formulation aspect and expected to be applied maximally in its implementation. Moreover, in relation with the weakness of the law enforcement, it turns out that there is only a few cases brought before the court, and if it is then processed, the punishment that is sentenced for the criminal is very minimize. Based on this research results, the writer would like to view a recommendation, so that the government as well as related agency could increase the law enforcement towards the case of human trafficking especially women and children, have a tight supervision in various vulnerable territories for this type of case, strengthened the international, government agency, and NGO co-ordination and co-operation, as well as immediately legalize the Draft on Elimination of Human Trafficking.