To analyze the relationship between exposure to xylene as organic solvents and neurotoxic symptoms as affect of xylene exposure between paint manufacture workers. Fourty-five male workers completed a symptom questionnaire 18 Germany version. Fourteen workers underwent the positive neurotoxic symptoms from the questionnaire results. In chi-square tests, confounding variables for working period, smoking habits, exercise habits, duration of xylene exposure, usage of respiratory protection, and historical disease were found a not significant relation with the symptoms of neurotoxic with affect of xylene exposure. The relation between level of exposure and age factor, in both correlation and linier regression analysis were poor relation with the symptoms of neurotoxic with affect of xylene exposure.The results suggest that a symptom and some behavioral changes shows the neurotoxic effects to low levels of xylene exposure. However, no consistent pattern was observed in regard to the effects of xylene exposure on neurobehavioral dysfunction, in regards with the confounding factors that studied.

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Untuk menganalisis hubungan antara pajanan xylene sebagai pelarut organik dan gejala neurotoksik yang diakibatkan pajanan xylene pada pekerja pembuatan cat di PT. X tahun 2012. Empat puluh lima pekerja laki-laki menyelesaikan kuesioner Q18 versi Jerman. Empat belas pekerja mengalami gejala neurotoksik positif dari hasil kuesioner. Dalam uji chi-square, variabel confounding untuk masa kerja, kebiasaan merokok, kebiasaan olahraga, lama pajanan per minggu, penggunaan perlindungan pernapasan, dan riwayat penyakit ditemukan tidak berhubungan signifikan dengan gejala neurotoksik akibat pajanan xylene. Hubungan antara tingkat pajanan xylene dan faktor usia, baik lewat uji korelasi dan analisis regresi linier menunjukkan hubungan yang lemah dengan gejala neurotoksik akibat pajanan xylene.Hasil penelitian menunjukkan bahwa gejala neurotoksik dan beberapa perubahan perilaku terjadi pada pajanan xylene tingkat rendah. Namun, tidak ada gambaran yang menunjukkan pola yang linier yang diamati sehubungan dengan efek pajanan xylene pada gangguan neurobehavioral, berkaitan dengan faktor-faktor pengganggu yang dipelajari.