Menopause merupakan berhentinya menstruasi secara permanen yang disebabkan hilangnya fungsi folikel-folikel sel-sel telur. Wanita yang memasuki menopause mengalami penurunan hormon estrogen yang menyebabkan wanita mengalami keluhan-keluhan atau gangguan yang mengganggu aktivitas sehari-hari, bahkan menurunkan kualitas hidupnya. Penggunaan kontrasepsi pil memiliki keterkaitan dengan penundaan usia dan keluhan menopause. Penelitian ini meneliti hubungan antara penggunaan kontrasepsi pil terhadap usia menopause. Penelitian ini menggunakan desain cross sectional. Populasi pada penelitian ini adalah wanita menopause di Posbindu Kota Depok. Sampel pada penelitian ini adalah wanita menopause yang berusia 45 sampai 60 tahun. Teknik pengambilan sampel secara Purposive Sampling subjek dengan besar sampel 407 orang. Analisis multivariat pada penelitian ini menggunakan cox proportional hazard model. Hasil analisis multivariat menunjukkan tidak ada hubungan antara lama penggunaan kontrasepsi pil terhadap usia menopause baik sebelum maupun sesudah dikontrol variabel kovariat yaitu tingkat pendidikan. Namun demikian masih diperlukan penelitian lain dengan menggunakan desain penelitian kohort prospektif untuk dapat melihat hubungan temporal antara lama penggunaan kontrasepsi pil terhadap usia menopause.

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Menopause is marked with the permanent cessation of menstruation due to the loss of follicles. Earlier menopause will be likely to increase the risk factors relating to declined estrogen level, such as osteoporosis that can lead to early death. A woman entering menopause period often experiences declined estrogen hormone that causes her to have complaints or disturbances that hinder her daily activities and even reduce her quality of life. However, the use of oral contraceptive poses a correlation with the postponing of menopause age and complaints. The primary purpose of this study was to examine the relation of oral contraceptive use and age at menopause. This was an observational study with cross-sectional study design. Population in this study was all menopausal women in Posbindu, Depok. The sample was menopausal women among 45-60 years old. Sample was 407 menopausal women taken Purposive Sampling. The data was analysed by cox?s proportional hazard analysed. The longer use of oral contraceptive was not associated with age at menopause before and after adjusted for confounding variable (education). However, another similar studies was still needed with prospective kohort study design to know temporality causal of longer use of oral contraceptive and age at menopause.