Penelitian dilakukan untuk mengetahui kemampuan antagonisme enam spesies khamir filum Basidiomycota dari tanaman saeh (Broussonetia papyrifera Vent.) asal Bandung terhadap kapang Aspergillus spp. UICC. Pengujian menggunakan metode co-culture dalam medium Potato Dextrose Broth pH 5 pada suhu 30° C selama empat hari inkubasi. Khamir Cryptococcus luteolus UICC Y-461, Cryptococcus rajasthanensis UICC Y-458, Cryptococcus zeae UICC Y-463, Rhodotorula dairenensis UICC Y-457, Rhodotorula glutinis UICC Y-454, dan Rhodotorula mucilaginosa UICC Y-466 memiliki kemampuan antagonisme terhadap kapang Aspergillus spp. UICC. Cryptococcus luteolus UICC Y-461 merupakan khamir antagonis paling potensial karena mengalami peningkatan panjang sel rata-rata dan lebar sel rata-rata tertinggi ketika ditumbuhkan bersama Aspergillus niger UICC yaitu sebesar 9,88% dan 14,17%, mengalami peningkatan panjang sel rata-rata tertinggi ketika ditumbuhkan bersama Aspergillus ochraceus UICC yaitu sebesar 18,43%, memiliki kemampuan tertinggi dalam menghambat pertumbuhan kapang Aspergillus spp. UICC yaitu sebesar 100% (menyebabkan mortalitas kapang sebesar 100%), dan mengalami peningkatan jumlah sel tertinggi ketika ditumbuhkan bersama Aspergillus terreus UICC yaitu sebesar 41,62% pada inkubasi hari ke-4.

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The antagonism activity of six species of Basidiomycota yeasts from saeh plant (Broussonetia papyrifera Vent.) from Bandung against Aspergillus spp. UICC were investigated. The antagonism test was carried out by using co-culture method in Potato Dextrose Broth of pH 5 for four days at 30° C. Result showed that Cryptococcus luteolus UICC Y-461, Cryptococcus rajasthanensis UICC Y-458, Cryptococcus zeae UICC Y-463, Rhodotorula dairenensis UICC Y-457, Rhodotorula glutinis UICC Y-454, and Rhodotorula mucilaginosa UICC Y-466 were antagonists. Cryptococcus luteolus UICC Y-461 is the most potential antagonistic yeast because of the highest increase in average cell length and average cell width when grown with Aspergillus niger UICC by 9.88% and 14.17%, the highest increase in average cell length when grown with Aspergillus ochraceus UICC by 18.43%, the highest inhibition of growth of Aspergillus spp. UICC by 100% (caused 100% mortality of moulds), and increase the number of yeast cells when grown with Aspergillus terreus UICC by 41.62% at day-4.