Juvenile hypertrophy of the breast (JHB) merupakan gigantomastia unilateral atau bilateral pada wanita peripubertal dan merupakan kasus jarang. Kelainan ini terbatas pada payudara berupa pertumbuhan dan perkembangan yang tidak normal. Pembesaran payudara bilateral atau unilateral tidak hanya mengakibatkan gangguan fisik tetapi juga psikis. Etiologinya sulit ditentukan, tetapi kelainan ini menggambarkan adanya hipersensitifitas organ akibat gangguan regulasi endokrin. Terapi terbaik berupa pembedahan yaitu mastektomi atau mammaplasti reduksi. Laporan ini menyajikan kasus seorang wanita berusia 30 tahun dengan JHB. Pertumbuhan payudara kirinya dimulai saat pubertas dan terus membesar selama setahun. Operasi dilaksanakan berupa reduksi mammaplasti dengan wise pattern based design. Setelah dua tahun pasien tidak memiliki tanda-tanda rekurensi dan kedua payudaranya tampak simetris dengan parut yang memuaskan.

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Abstract
Juvenile hypertrophy of the breast (JHB) is a rare condition leading to gigantomastia unilaterally or bilaterally in peripubertal females. The pathology is limited usually to the breast, with otherwise normal growth and development and without any other deformities. The rapid bilateral or unilateral growth of the breast in adolescent girls leads to severe physical and psychological problems. The etiology remains elusive, but it is believed to represent an end-organ hypersensitivity during a period of intense endocrine regulatory stress. The best treatment is surgical whereas the younger patients better treated with mastectomy to anticipate the high recurrency rate, while older women is best treated with reduction mammaplasty. We report one case of a woman who had a unilateral JHB. The growth of the left breast started in her pubertal age and kept growing for one year. She was treated surgically with Wise pattern based design. After two years, she had no recurrent enlargement and aesthetically, the symmetry of both breasts is achieved with a satisfying scar.