Kitosan adalah salah satu contoh polimer yang memiliki bobot molekul besar dengan gugus amina dan gugus hidroksil, yang merupakan gugus reaktif. Gugus hidroksil ini terikat secara primer pada atom karbon nomor 6 dan secara sekunder terikat pada atom karbon nomor 3 sehingga dapat dimanfaatkan dalam proses modifikasi. Pada penelitian ini, kitosan direaksikan dengan anhidrida suksinat untuk dilihat selektivitasnya terhadap gugus-gugus reaktif tersebut, dengan memvariasikan massa anhidrida suksinat dan suhu reaksi. Hasil sintesis ini dikarakterisasi menggunakan FTIR (Fourier Transform Infra Red) dan 1H-NMR (Nuclear Magnetic Resonance). Analisis menggunakan FTIR pada perbandingan massa kitosan dengan suksinat 1 : 0,2 g hanya menunjukkan puncak serapan karbonil amida pada bilangan gelombang 1681 cm-1 dan hasil karakterisasi menggunakan 1H-NMR menunjukkan puncak pergeseran kimia pada rentang 2,5ppm-2,7ppm. Hasil analisis keduanya mengindikasikan anhidrida suksinat bereaksi dengan gugus amina. Pada perbandingan inilah reaksi kitosan dengan anhidrida suksinat selektif pada gugus amina.

---

Chitosan is one example of polymer with large moleculer weight. It has amino groups and hydroxyl groups which are primarily bound to carbon atom number 6 and secondary hydroxyl group in carbon atom number 3, they are reactive groups. They can also be used in the modification process. In this research, chitosan is reacted with succinic anhydride to observe the selectivity of these reactive groups by varying masses of succinic anhydride and the temperatur of reaction. The product of this synthesis is characterized with FTIR (Fourier Transform Infra Red ) and 1H-NMR (Nuclear Magnetic Resonance). Based on the result obtained with FTIR, when the mass ratio 1: 0,2 g, carbonyl peak appears only in the 1681 cm-1. Results of 1H-NMR characterization shows chemical shift at 2.4 to 2.8 ppm indicates that succinic anhydride reacts with the amine group. So in this ratio, chitosan which is reacted with succinic anhydride selective in amino groups.;Chitosan is one example of polymer with large moleculer weight. It has amino groups and hydroxyl groups which are primarily bound to carbon atom number 6 and secondary hydroxyl group in carbon atom number 3, they are reactive groups. They can also be used in the modification process. In this research, chitosan is reacted with succinic anhydride to observe the selectivity of these reactive groups by varying masses of succinic anhydride and the temperatur of reaction. The product of this synthesis is characterized with FTIR (Fourier Transform Infra Red ) and 1H-NMR (Nuclear Magnetic Resonance). Based on the result obtained with FTIR, when the mass ratio 1: 0,2 g, carbonyl peak appears only in the 1681 cm-1. Results of 1H-NMR characterization shows chemical shift at 2.4 to 2.8 ppm indicates that succinic anhydride reacts with the amine group. So in this ratio, chitosan which is reacted with succinic anhydride selective in amino groups.