UI - Tugas Akhir :: Kembali

UI - Tugas Akhir :: Kembali

Hubungan volume lemak perikardial dengan derajat stenosis aterosklerosis arteri koronaria pada pasien di RSCM yang menjalani pemeriksaan DSCT jantung = Correlation of pericardial fat volume and stenotic degree of atherosclerotic coronary artery of patient at Cipto Mangunkusumo hospital who underwent DSCT cardiac examination

Elena Maliani; (Fakultas Kedokteran Universitas Indonesia, 2013)

 Abstrak

[Tujuan: Menentukan hubungan antara volume lemak perikardial dengan derajat
stenosis aterosklerosis arteri koronaria pada pasien yang menjalani pemeriksaan
dual-source CT jantung di RSCM, sehingga dapat dilakukan penentuan titik
potong volume lemak perikardial yang dapat digunakan untuk mendeteksi derajat
stenosis aterosklerosis arteri koronaria hanya dengan menghitung volume lemak
perikardial saja.
Metode: Analisa retrospektif hasil CT jantung dari 53 pasien yang diambil secara
consecutive, meliputi penilaian derajat stenosis aterosklerosis arteri koronaria dan
penghitungan volume lemak perikardial. Derajat stenosis aterosklerosis arteri
koronaria dikelompokkan menjadi tidak ada stenosis, ringan, sedang dan berat,
berdasarkan metode indeks prognosis Duke. Volume lemak perikardial dihitung
dalam satuan cm3 dengan menggunakan perangkat lunak analisa volume pada
cardiac workstation (Siemens, Leonardo), lemak perikardial adalah gabungan
antara lemak epikardial dengan lemak parakardial. Analisa statistik penelitian ini
menggunakan uji Anova.
Hasil: Terdapat hubungan positif antara volume lemak perikardial dengan
stenosis arteri koronaria derajat sedang pada pasien di RSCM yang menjalani
pemeriksaan DSCT jantung. Titik potong volume lemak perikardial untuk
mendeteksi stenosis arteri koronaria derajat sedang adalah 185 cm3 (≥ 185 cm3
dan < 185 cm3), dengan nilai sensitifitas 81,8 %, spesifisitas 63,15 %, akurasi 70
% dan OR 7,71 pada 95 % interval kepercayaan 1,03 – 72,06.
Kesimpulan: Volume lemak perikardial dapat digunakan untuk menentukan
stenosis arteri koronaria derajat sedang, sehingga dapat dipakai sebagai suatu
acuan deteksi dini stenosis arteri koronaria bagi pasien yang beresiko terhadap
kejadian PJK.;Purpose: to determine the correlation between pericardial fat volume and stenosis
grade of atherosclerotic coronary artery in patients who underwent dual-source
cardiac CT in Cipto Mangunkusumo hospital and cut off point of pericardial fat
volume that can be used to determine stenosis grade of atherosclerotic coronary
artery.
Methods : Retrospective analysis of 53 consecutive patients who underwent dualsource
cardiac CT in Cipto Mangunkusumo hospital, the assessment was include
stenosis grade of atherosclerotic coronary artery and pericardial fat volume.
Stenosis grade were classified as no stenosis, mild, moderate and severe based on
prognostic index Duke. Pericardial fat volume was measured in cm3 using the
Volume Analysis software tool of our cardiac workstation (Siemens, Leonardo),
pericardial fat defined as epicardial fat plus paracardial fat. Statisticall analysis
were performed with Anova test.
Results : There was positive correlation between pericardial fat volume and
moderate stenosis of atherosclerotic coronary artery in patients who underwent
dual-source cardiac CT in Cipto Mangunkusumo hospital. A cut-off value of 185
cm3 (≥ 185 cm3 and <185 cm3) determined a sensitivity and specivicity to detect
moderate stenosis of 81,8% and 63,15%,, with accuracy of 70% and OR 7,71 in
95% confident interval 1,03 – 72,06.
Conclusions : Pericardial fat volume can be use to determine moderate stenosis of
atherosclerotic coronary artery in patients who underwent dual-source cardiac CT
in Cipto Mangunkusumo hospital due to early detection for coronary stenotic
condition in patient who have higher risk for CAD., Purpose: to determine the correlation between pericardial fat volume and stenosis
grade of atherosclerotic coronary artery in patients who underwent dual-source
cardiac CT in Cipto Mangunkusumo hospital and cut off point of pericardial fat
volume that can be used to determine stenosis grade of atherosclerotic coronary
artery.
Methods : Retrospective analysis of 53 consecutive patients who underwent dualsource
cardiac CT in Cipto Mangunkusumo hospital, the assessment was include
stenosis grade of atherosclerotic coronary artery and pericardial fat volume.
Stenosis grade were classified as no stenosis, mild, moderate and severe based on
prognostic index Duke. Pericardial fat volume was measured in cm3 using the
Volume Analysis software tool of our cardiac workstation (Siemens, Leonardo),
pericardial fat defined as epicardial fat plus paracardial fat. Statisticall analysis
were performed with Anova test.
Results : There was positive correlation between pericardial fat volume and
moderate stenosis of atherosclerotic coronary artery in patients who underwent
dual-source cardiac CT in Cipto Mangunkusumo hospital. A cut-off value of 185
cm3 (≥ 185 cm3 and <185 cm3) determined a sensitivity and specivicity to detect
moderate stenosis of 81,8% and 63,15%,, with accuracy of 70% and OR 7,71 in
95% confident interval 1,03 – 72,06.
Conclusions : Pericardial fat volume can be use to determine moderate stenosis of
atherosclerotic coronary artery in patients who underwent dual-source cardiac CT
in Cipto Mangunkusumo hospital due to early detection for coronary stenotic
condition in patient who have higher risk for CAD.]

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Jenis Koleksi : UI - Tugas Akhir
No. Panggil : SP-pdf
Entri utama-Nama orang :
Program Studi :
Subjek :
Penerbitan : [Place of publication not identified]: Fakultas Kedokteran Universitas Indonesia, 2013
Bahasa : ind
Sumber Pengatalogan : LibUI ind rda
Tipe Konten :
Tipe Media :
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Deskripsi Fisik : xii, 46 hlm. : ill. ; 28 cm. + lamp.
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 3
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