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Perbandingan carotid stiffness pada pasien penyakit jantung koroner stabil dengan dan tanpa diabetes mellitus tipe 2 = Comparison of carotid stiffness between stable coronary artery disease with and without type 2 diabetes mellitus

Hengky Gosal; (Fakultas Kedokteran Universitas Indonesia, 2013)

 Abstrak

[Latar Belakang: Carotid stiffness (CS) merupakan perubahan fungsional pada
arteri karotis akibat aterosklerosis. Diabetes mellitus tipe 2 (DMT2) akan
mempercepat dan memperburuk aterosklerosis sehingga meningkatkan risiko
kejadian kardiovaskular. Sampai saat kini belum ada data di Indonesia tentang CS
pada pasien penyakit jantung koroner (PJK) stabil dengan DMT2 yang
menggunakan sistem otomatis echotracking ultrasound berbasis frekuensi radio.
Penelitian ini bertujuan untuk membandingkan CS pada pasien PJK stabil dengan
dan tanpa DMT2.
Metode: Comparative cross-sectional antara kelompok pasien PJK stabil dengan
dan tanpa pasien DMT2. Pemeriksaan CS dilakukan dengan posisi pasien
berbaring telentang secara non-invasif pada 1 cm sebelum bulbus arteri karotis
kiri dan kanan menggunakan automatic echotracking radiofrequency-based
ultrasound dengan probe linear 3-13 MHz. Pengukuran CS dilakukan sebanyak
enam kali pada masing-masing sisi arteri karotis dengan nilai tertinggi rerata
carotid Pulse Wave Velocity (car-PWV) sebagai nilai CS individu.
Hasil: Dari total 42 pasien (21 pasang) yang diperiksa didapatkan nilai rerata car-
PWV pasien PJK stabil dengan DMT2 lebih tinggi dibandingkan pasien PJK stabil
tanpa DMT2 (9,8±1,3m/s vs 6,7±1,3m/s, p< 0,001).
Kesimpulan: Nilai carotid stiffness pasien PJK stabil dengan DMT2 lebih tinggi
dibandingkan pasien PJK stabil tanpa DMT2.;Background: Carotid stiffness (CS) represents the functional changes in carotid
arteries due to atherosclerosis. Progression of atherosclerosis was more
accelerated in type 2 diabetes mellitus (T2DM) compared to non-diabetic patient,
thus increasing the risk of cardiovascular events. Until now there is no data of CS
in stable coronary artery disease (CAD) with T2DM in Indonesia using automatic
echotracking radiofrequency-based ultrasound. The aim of this study was to
compare CS in stable CAD with and without T2DM patient.
Method: Comparative cross-sectional between group of stable CAD with and
without T2DM patients. CS was measured in patient lying down non-invasively at
1 cm proximal to bulbus of the left and right carotid artery using
automatICechotracking radiofrequency-based ultrasound system, 3-13 MHz linear
probe. The highest mean carotid pulse wave velocity (car-PWV) value of six
measurements of both side was used as an individual CS.
Result: Total 42 patients (21 pairs) was examined. Mean value of car-PWV stable
CAD with T2DM patient is higher than stable CAD without T2DM patient (9.8
1.3 m/s vs. 6.7 1.3 m/s, p<0.001)
Conclusion: Carotid stiffness value of stable CAD with T2DM patient is higher
than stable CAD without T2DM patient.;Background: Carotid stiffness (CS) represents the functional changes in carotid
arteries due to atherosclerosis. Progression of atherosclerosis was more
accelerated in type 2 diabetes mellitus (T2DM) compared to non-diabetic patient,
thus increasing the risk of cardiovascular events. Until now there is no data of CS
in stable coronary artery disease (CAD) with T2DM in Indonesia using automatic
echotracking radiofrequency-based ultrasound. The aim of this study was to
compare CS in stable CAD with and without T2DM patient.
Method: Comparative cross-sectional between group of stable CAD with and
without T2DM patients. CS was measured in patient lying down non-invasively at
1 cm proximal to bulbus of the left and right carotid artery using
automatICechotracking radiofrequency-based ultrasound system, 3-13 MHz linear
probe. The highest mean carotid pulse wave velocity (car-PWV) value of six
measurements of both side was used as an individual CS.
Result: Total 42 patients (21 pairs) was examined. Mean value of car-PWV stable
CAD with T2DM patient is higher than stable CAD without T2DM patient (9.8
1.3 m/s vs. 6.7 1.3 m/s, p<0.001)
Conclusion: Carotid stiffness value of stable CAD with T2DM patient is higher
than stable CAD without T2DM patient., Background: Carotid stiffness (CS) represents the functional changes in carotid
arteries due to atherosclerosis. Progression of atherosclerosis was more
accelerated in type 2 diabetes mellitus (T2DM) compared to non-diabetic patient,
thus increasing the risk of cardiovascular events. Until now there is no data of CS
in stable coronary artery disease (CAD) with T2DM in Indonesia using automatic
echotracking radiofrequency-based ultrasound. The aim of this study was to
compare CS in stable CAD with and without T2DM patient.
Method: Comparative cross-sectional between group of stable CAD with and
without T2DM patients. CS was measured in patient lying down non-invasively at
1 cm proximal to bulbus of the left and right carotid artery using
automatICechotracking radiofrequency-based ultrasound system, 3-13 MHz linear
probe. The highest mean carotid pulse wave velocity (car-PWV) value of six
measurements of both side was used as an individual CS.
Result: Total 42 patients (21 pairs) was examined. Mean value of car-PWV stable
CAD with T2DM patient is higher than stable CAD without T2DM patient (9.8
1.3 m/s vs. 6.7 1.3 m/s, p<0.001)
Conclusion: Carotid stiffness value of stable CAD with T2DM patient is higher
than stable CAD without T2DM patient.]

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 Metadata

Jenis Koleksi : UI - Tesis Membership
No. Panggil : T55967
Entri utama-Nama orang :
Program Studi :
Subjek :
Penerbitan : [Place of publication not identified]: Fakultas Kedokteran Universitas Indonesia, 2013
Bahasa : ind
Sumber Pengatalogan : libui ind rda
Tipe Konten :
Tipe Media :
Tipe Carrier :
Deskripsi Fisik : xvi, 52 hlm. : ill. ; 30 cm. + lamp.
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 3
  • Ketersediaan
  • Ulasan
  • Sampul
No. Panggil No. Barkod Ketersediaan
T55967 15-23-85833081 TERSEDIA
Ulasan:
Tidak ada ulasan pada koleksi ini: 20367178
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