[Latar belakang—Untuk menentukan sindrom epilepsi selain anamnesis juga diperlukan adanya bukti gelombang elektroensefalografi (EEG) yang spesifik. Salah satu cara dengan melakukan teknik hiperventilasi (HV) untuk
membangkitkan abnormalitas gelombang EEG. Stimulasi hiperventilasi dapat menimbulkan bangkitan umum dan parsial. Dengan mengetahui hal tersebut dapat menentukan terapi dan prognosis pasien epilepsi.
Tujuan Mengetahui waktu terjadinya gelombang epileptiform tertinggi selama durasi HV 5 menit pada pemeriksaan EEG untuk meningkatkan manfaat pemeriksaan penunjang yang mendukung kearah diagnosis epilepsi.
Metode Penelitian ini merupakan penelitian prospektif secara historis menggunakan teknik hiperventilasi selama 5 menit saat pemeriksaan EEG untuk mencari aktivitas epileptiform pada EEG pasien epilepsi dan atau dengan bangkitan epileptik di Rumah Sakit Cipto Mangunkusumo.
Hasil— Dari 70 subyek penelitian didapatkan paling banyak tipe bangkitan parsial dengan sindrom epilepsi lobus temporal sebagai jenis sindrom terbanyak.
Pada menit ke-2 stimulasi hiperventilasi terjadi aktivitas epileptiform paling banyak sedangkan pada menit ke-1 dan ke-5 terdapat aktivitas epileptiform paling sedikit. Terdapat hubungan yang bermakna antara bangkitan terkontrol
obat dengan aktivitas epileptiform dan atau dengan bangkitan epileptik (p=0.043).
Pada subyek yang tidak terkontrol obat mempunyai resiko mengalami aktivitas epileptiform 0.22 kali lebih besar dibandingkan dengan yang terkontrol obat.
Sedangkan faktor lainnya seperti jenis sindrom, tipe, onset dan frekuensi bangkitan tidak menunjukkan perbedaan yang bermakna (p=0.119; p=0.392; p=0.636; p=1.000).
Simpulan— Penelitian saat ini menunjukkan aktivitas epileptiform paling banyak terdapat pada menit ke-2 stimulasi hiperventilasi. Terdapat kecenderungan pasien
epilepsi yang tidak terkontrol obat mempunyai resiko mengalami aktivitas epileptiform 0.22 kali lebih besar dibandingkan dengan yang terkontrol obat pada
pemeriksaan hiperventilasi selama 5 menit
Background Diagnosis of epilepsy syndrome beside clinical judgement is alsorequired specific wave evidence from electroencephalography (EEG). One of themethod is to perform the hyperventilation techniques (HV) which can generatewave EEG abnormalities. Stimulation of hyperventilation can cause general andpartial seizures. By knowing these things, we can determine further treatment andprognosis of the epilepsy patients.Objective— To determine the highest timing of the wave emergence during 5minutes hyperventilation in the EEG to improve the benefits of supporting theinvestigation towards the diagnosis of epilepsy.Methods— The study was conducted using a historical prospective study design.All samples were collected in Cipto Mangunkusumo Hospital and undergo EEGwith 5 minutes hyperventilation technique to look for epileptiform activity.Results— From 70 subjects obtained, most of it are partial seizures with temporallobe epilepsy syndrome as the most syndrome types. In the 2nd minute ofhyperventilation stimulation occurs epileptiform activity most widely while atminute 1 and 5 are less epileptiform activity. There is a significant relationshipbetween controlled drug patients with epileptiform activity and or with epilepticseizures (p = 0.043). In subjects who are at risk of uncontrolled drug hadepileptiform activity 0.22 times larger than the controlled drug. While otherfactors such as the type of syndrome, type, onset and frequency of seizure showedno significant difference (p = 0.119, p = 0.392, p = 0636, p = 1.000).Conclusions— The present study showed epileptiform activity are most commonin the 2nd minute stimulation hyperventilation. There is a tendency ofuncontrolled epilepsy patients who are at risk of experiencing epileptiformactivity 0.22 times greater than the drug controlled patients during 5 minuteshyperventilation techniques., Background— Diagnosis of epilepsy syndrome beside clinical judgement is alsorequired specific wave evidence from electroencephalography (EEG). One of themethod is to perform the hyperventilation techniques (HV) which can generatewave EEG abnormalities. Stimulation of hyperventilation can cause general andpartial seizures. By knowing these things, we can determine further treatment andprognosis of the epilepsy patients.Objective— To determine the highest timing of the wave emergence during 5minutes hyperventilation in the EEG to improve the benefits of supporting theinvestigation towards the diagnosis of epilepsy.Methods— The study was conducted using a historical prospective study design.All samples were collected in Cipto Mangunkusumo Hospital and undergo EEGwith 5 minutes hyperventilation technique to look for epileptiform activity.Results— From 70 subjects obtained, most of it are partial seizures with temporallobe epilepsy syndrome as the most syndrome types. In the 2nd minute ofhyperventilation stimulation occurs epileptiform activity most widely while atminute 1 and 5 are less epileptiform activity. There is a significant relationshipbetween controlled drug patients with epileptiform activity and or with epilepticseizures (p = 0.043). In subjects who are at risk of uncontrolled drug hadepileptiform activity 0.22 times larger than the controlled drug. While otherfactors such as the type of syndrome, type, onset and frequency of seizure showedno significant difference (p = 0.119, p = 0.392, p = 0636, p = 1.000).Conclusions— The present study showed epileptiform activity are most commonin the 2nd minute stimulation hyperventilation. There is a tendency ofuncontrolled epilepsy patients who are at risk of experiencing epileptiformactivity 0.22 times greater than the drug controlled patients during 5 minuteshyperventilation techniques.]