UI - Tesis Membership :: Kembali

UI - Tesis Membership :: Kembali

Skrining darah donor dengan rapid test antigen rapid test antibodi mikroskopik dan polymerase chain reaction terhadap parasit malaria di Kota Ambon = Screening of blood donors with antigen rapid test rapid antibody test microscopic and polymerase chain reaction against malaria parasite in Ambon City

Louhenapessy, Julianti Nethasia; Inge Sutanto, supervisor; Ria Syafitri Evi Gantini, supervisor; Yuyun Siti Maryuningsih Soedarmono, examiner; Beti Ernawati Dewi, examiner; Leily Trianty, examiner (Fakultas Kedokteran Universitas Indonesia, 2014)

 Abstrak

[ABSTRAK
Skrining darah pendonor di Indonesia terhadap malaria belum dilakukan dengan pemeriksaan laboratorium. Kemungkinan resiko penularan malaria melalui darah donor dapat terjadi dan membahayakan jiwa resipien. Malaria di kota Ambon berdasarkan Annual Parasite Incidence adalah 4,49? termasuk High Case Incidence (HCI).
Penelitian ini bertujuan mengetahui prevalensi malaria dengan berbagai pemeriksaan laboratorium di kota Ambon. Dikumpulkan sebanyak 550 donor di Unit transfusi darah PMI Ambon dalam kurun waktu 3 bulan dan dilakukan berbagai pemeriksaan. Hasilnya memperlihatkan tidak satupun terdeteksi positif dengan pemeriksaan mikroskopik maupun rapid test antigen Pf HRP2-pan aldolase atau Pf HRP-2- PvLDH. Duapuluh dua donor terbukti mengandung immunoglobulin P. falciparum dengan rapid test antibodi. Lima donor lain positif dengan PCR menggunakan 18S rRNA. Penelitian ini membuktikan adanya potensi penularan malaria dari darah donor sebesar 4.9% di Pulau Ambon.

ABSTRACT
Screening of blood donors in Indonesia against malaria with laboratory tests have not been done . Possible risk of malaria transmission through donated blood may occur and endanger the lives of recipients . Malaria in the city of Ambon by Annual Parasite Incidence was 4.49 ? including High Case Incidence (HCI). This study aims to determine the prevalence of malaria with a several laboratory tests in the city of Ambon . Collection of total 550 donors at Red Cross blood transfusion unit Ambon, was carried out for a period of 3 months and followed by various examinations. The results showed none detected positive by microscopic examination or antigen rapid test PfHRP2-aldolase or PfHRP2-LDH. Twenty-two donors were found to contain P. falciparum with immunoglobulin antibody rapid test, in addition five other donors positive by PCR using 18S rRNA . This study showed that the potency of malaria transmission by blood donors was 4.9% in the island of Ambon .;Screening of blood donors in Indonesia against malaria with laboratory tests have not been done . Possible risk of malaria transmission through donated blood may occur and endanger the lives of recipients . Malaria in the city of Ambon by Annual Parasite Incidence was 4.49 ? including High Case Incidence (HCI). This study aims to determine the prevalence of malaria with a several laboratory tests in the city of Ambon . Collection of total 550 donors at Red Cross blood transfusion unit Ambon, was carried out for a period of 3 months and followed by various examinations. The results showed none detected positive by microscopic examination or antigen rapid test PfHRP2-aldolase or PfHRP2-LDH. Twenty-two donors were found to contain P. falciparum with immunoglobulin antibody rapid test, in addition five other donors positive by PCR using 18S rRNA . This study showed that the potency of malaria transmission by blood donors was 4.9% in the island of Ambon ., Screening of blood donors in Indonesia against malaria with laboratory tests have not been done . Possible risk of malaria transmission through donated blood may occur and endanger the lives of recipients . Malaria in the city of Ambon by Annual Parasite Incidence was 4.49 ? including High Case Incidence (HCI). This study aims to determine the prevalence of malaria with a several laboratory tests in the city of Ambon . Collection of total 550 donors at Red Cross blood transfusion unit Ambon, was carried out for a period of 3 months and followed by various examinations. The results showed none detected positive by microscopic examination or antigen rapid test PfHRP2-aldolase or PfHRP2-LDH. Twenty-two donors were found to contain P. falciparum with immunoglobulin antibody rapid test, in addition five other donors positive by PCR using 18S rRNA . This study showed that the potency of malaria transmission by blood donors was 4.9% in the island of Ambon .]

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 Metadata

Jenis Koleksi : UI - Tesis Membership
No. Panggil : T-Pdf
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Entri tambahan-Nama badan :
Program Studi :
Subjek :
Penerbitan : Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
Bahasa : ind
Sumber Pengatalogan : LibUI ind rda
Tipe Konten : text
Tipe Media : computer
Tipe Carrier : online resource
Deskripsi Fisik : xvi, 55 pages : illustration ; 28 cm + appendix
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI
  • Ketersediaan
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No. Panggil No. Barkod Ketersediaan
T-Pdf 15-17-762663182 TERSEDIA
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Tidak ada ulasan pada koleksi ini: 20390193
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