The present volume brings together twelve essays by leading specialists which explore the history and philosophical significance of this form of skepticism. They discuss some thorny questions concerning ancient pyrrhonism, explore its influence on certain modern thinkers, and examine it in relation to contemporary analytic philosophy. The essays combine historical and exegetical analysis with an assessment of the philosophical merits of the pyrrhonian outlook, with the aim of understanding it both in its historical context and in connection with contemporary concerns. This volume, the first entirely devoted to a detailed study of the pyrrhonian tradition, is intended to open up new exegetical and philosophical perspectives on pyrrhonism and to motivate further examination of certain difficult issues.