This book is that the U.S.-Mexico border region is subject to systematic oppression and that the so-called social pathologies that we see in the region are by-products of social and economic injustice in the form of labor exploitation, environmental racism, immigration militarism, institutional sexism and discrimination, health inequities, a political economy based on low-wage labor, and the globalization of labor and capital. The chapters address a variety of examples of injustice in the areas of environment, health disparity, migration unemployment, citizenship, women and gender violence, mental health, and drug violence. The book proposes a pathway to development.