Latar Belakang: Stres dapat diimplikasikan sebagai faktor risiko terhadap penyakit periodontal, yang dapat dilihat melalui kadar Interleukin-1β (IL-1 β). Tujuan: Menganalisa hubungan stres akademik terhadap status penyakit periodontal berdasarkan kadar IL-1β pada mahasiswa FKG UI program profesi. Material dan metode:Pemeriksaan Dental Environtmental Stress (DES), indeks periodontal (indeks modifikasi Russel), dan kadar IL-1β dengan ELISA assay terhadap 38 subjek. Hasil: Perbedaan bermakna pada hubungan antara status penyakit periodontal dengan kadar IL-1βmahasiswa profesi dokter gigiFKG UI. Kesimpulan: Terdapat hubungan antara status penyakit periodontal dengan kadar IL-1β, namun hubungannya dengan stres akademik belum dapat dibuktikan.

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Introduction: Stress condition was implicated as one of risk factor to periodontal disease, that can be assesed by Interleukin-1β (IL-1β) level.

Objectives: To analyzethe relationship between academical stress to periodontal status and IL-1β.

Material and methods: 38 subjects were measuredfor perceived stress using The Dental Environment Stress (DES); periodontal condition using modified Russel periodontal index, and level of IL-1β in GCFusing ELISA assay.

Results: A significant differences was only showed in the relationship between IL-1βto periodontal status.

Conclusion: There is a relationship between IL-1β level to periodontal status, but not to academic stress.