This book constitutes the refereed proceedings of the 6th International Symposium on Trustworthy Global Computing, TGC 2011, held in Aachen, Germany, in June 2011. The 14 revised full papers presented were carefully reviewed and selected from 25 submissions. The papers are organized in topical sections on modeling formalisms for concurrent systems, model checking and quantitative extensions thereof, semantics and analysis of modern programming languages, probabilistic models for concurrency, and testing and run-time verification.