The 53 revised papers presented together with 6 invited lectures were carefully reviewed and selected with an acceptance rate of under 29,8%. The CiE 2012 Turing Centenary Conference will be remembered as a historic event in the continuing development of the powerful explanatory role of computability across a wide spectrum of research areas. The papers presented at CiE 2012 represent the best of current research in the area, and forms a fitting tribute to the short but brilliant trajectory of Alan Mathison Turing. Both the conference series and the association promote the development of computability-related science, ranging over mathematics, computer science and applications in various natural and engineering sciences such as physics and biology, and also including the promotion of related non-scientific fields such as philosophy and history of computing.