[Penduduk di daerah kumuh memiliki kemungkinan terpajan mikroba patogen
yang lebih besar daripada penduduk yang tinggal di daerah di daerah non kumuh.
Hal ini dapat dipengaruhi oleh gaya hidup mereka. Apabila terpajan mikroba
patogen sistem imun tubuh akan terpicu untuk melawan patogen tersebut. Salah
satu bagian dari sistem imun tubuh manusia adalah imunoglobulin atau antibodi,
salah satu jenis globulin. Pembentukan globulin ini akan menekan sintesis jenisjenis
protein lain, salah satunya adalah albumin yang sangat diperlukan tubuh.
Oleh karena itu, dilakukan penelitian untuk membandingkan rasio albumin
globulin pada penduduk daerah kumuh dan non kumuh. Penelitian cross sectional
dilakukan pada bulan Desember 2014 yang melibatkan 40 orang sampel dari
daerah kumuh dan 40 orang dari daerah non kumuh dengan metode consecutive
sampling. Berdasarkan hasil pemeriksaan darah yang diuji dengan metode uji T
independen, rasio albumin globulin penduduk di daerah non kumuh lebih tinggi
dibanding rasio albumin globulin penduduk yang tinggal di daerah kumuh dengan
p = 0,000. Dari uji korelasi, didapatkan bahwa terdapat perbedaan antara rasio
albumin globulin dari sampel yang terinfeksi sejumlah jenis patogen dengan yang
tidak terinfeksi namun tidak bermakna secara statistik dengan p = 0,169 dan
koefisien korelasi ?0,113. Rasio prevalensi didapatkan 0,63 CI 95% (0,25-1,60).;People living inside of landfill area have a higher chance of being exposed to
pathogens compared to people living outside of landfill area. This can be affected
by their lifestyle. When exposed to pathogen, human?s immune system will be
triggered to combat the pathogens. Immunoglobulin or antibody, a kind of
globulin, is a part of the immune system. The synthesis of globulin will repress the
synthesis of other kinds of protein, one of them being albumin which is highly
needed in the human body. Therefore, a research was conducted to compare the
albumin globulin ratio in people living inside and outside of landfill area. The
cross sectional study was conducted on December 2014 and involved 40 subjects
from inside landfill area and 40 subjects from outside landfill areas using
consecutive sampling method. From blood examination result that has been tested
using T-test independent method, the albumin globulin ratio in people living
outside of landfill area was higher compared to people living inside of landfill
area with p = 0.000. From correlation test, there was a difference of albumin
globulin ratio between people infected with certain pathogens and those who were
not but was not considered statistically significant with p = 0.169 and correlation
coefficient of ?0.113. Prevalence ratio was 0.63 CI 95% (0.25-1.60)., People living inside of landfill area have a higher chance of being exposed to
pathogens compared to people living outside of landfill area. This can be affected
by their lifestyle. When exposed to pathogen, human’s immune system will be
triggered to combat the pathogens. Immunoglobulin or antibody, a kind of
globulin, is a part of the immune system. The synthesis of globulin will repress the
synthesis of other kinds of protein, one of them being albumin which is highly
needed in the human body. Therefore, a research was conducted to compare the
albumin globulin ratio in people living inside and outside of landfill area. The
cross sectional study was conducted on December 2014 and involved 40 subjects
from inside landfill area and 40 subjects from outside landfill areas using
consecutive sampling method. From blood examination result that has been tested
using T-test independent method, the albumin globulin ratio in people living
outside of landfill area was higher compared to people living inside of landfill
area with p = 0.000. From correlation test, there was a difference of albumin
globulin ratio between people infected with certain pathogens and those who were
not but was not considered statistically significant with p = 0.169 and correlation
coefficient of –0.113. Prevalence ratio was 0.63 CI 95% (0.25-1.60).]
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