[Penelitian ini dilakukan pada perusahaan farmasi di Indonesia. Masalah yang dialami oleh perusahaan tersebut adalah rendahnya yield pada lini produksi effervescent selama tahun 2014. Penyelesaian masalah ini dilakukan dengan menggunakan metode Lean-DMAIC. Berdasarkan analisis yang dilakukan, dihasilkan beberapa perbaikan yang diimplementasikan pada mesin, operator, dan material. Hasil penerapan usulan perbaikan tersebut memberikan dampak yang positif bagi perusahaan, antara lain meningkatnya yield sebesar 3,59%, menurunnya waste cost komponen material sebesar 26,79%, dan menurunnya downtime mesin sebesar 74,30%.

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This study is conducted in one of the most well-known pharmaceutical company in Indonesia. Problem starts when effervescent line production yield was too low throughout 2014 so that the targeted yield could not be reached. This study applies Lean-DMAIC method to solve the problem. Lean-DMAIC analysis results in several improvements on machine, operators, and material. Result shows that the implemented improvements give several benefits for company, such as increasing 3,59% yield, reducing 26,79% material waste cost, and reducing 74,30% machine downtime.

, This study is conducted in one of the most well-known pharmaceutical company in Indonesia. Problem starts when effervescent line production yield was too low throughout 2014 so that the targeted yield could not be reached. This study applies Lean-DMAIC method to solve the problem. Lean-DMAIC analysis results in several improvements on machine, operators, and material. Result shows that the implemented improvements give several benefits for company, such as increasing 3,59% yield, reducing 26,79% material waste cost, and reducing 74,30% machine downtime.

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