[ABSTRAK
Latar Belakang: Belum ada hubungan konsisten antara kadar seng dalam serumdengan gangguan fungsi eksekutif pada anak dengan GPPH. Studi ini bertujuanuntuk mengidentifikasi perbedaan rerata kadar seng dalam serum pada anakGPPH dengan gangguan fungsi eksekutif, tanpa gangguan fungsi eksekutif andanak non GPPH, dan korelasi antara kadar seng dalam serum dengan fungsieksekutif pada anak GPPH.Metode. Penelitian ini adalah studi potong-lintang dengan kontrol. Sembilanpuluh anak dari dua Sekolah Dasar di Jakarta diambil secara acak sebagai subjekpenelitian yang dibagi dalam 30 anak GPPH dengan gangguan fungsi eksekutif,30 anak GPPH tanpa gangguan fungsi eksekutif, dan 30 anak non GPPH. Kadarseng dalam serum diperiksa dengan metode Inductively Coupled Plasma-MassSpectrophotometry. Fungsi eksekutif didapatkan melalui pemeriksaan BRIEFversi bahasa Indonesia. Analisis data menggunakan SPPS for Windows versi 20.Hasil. Dari seluruh subjek penelitian, 75% mengalami defisiensi seng. Ditemukan60% anak GPPH dengan gangguan fungsi eksekutif memiliki kadar seng tidaknormal. Rerata serum seng pada anak GPPH dengan gangguan fungsi eksekutifadalah 59.40 g/dL, pada anak GPPH tanpa gangguan fungsi eksekutif adalah55.36 g/dL, dan pada anak non GPPH adalah 52.93 g/dL. Tidak ada perbedaanbermakna pada rerata serum seng antara tiga kelompok (p = 0.119). Korelasiantara kadar seng pada anak GPPH dengan fungsi eksekutif adalah r=0.128.Kesimpulan. Kadar seng dalam serum tidak berhubungan secara langsung dengangangguan fungsi eksekutif, namun diduga berhubungan dengan gejala klinisGPPH. Perlu dilakukan penelitian lanjutan untuk mengetahui lebih jelas hubunganantara seng dalam serum dengan fungsi eksekutif pada anak dengan GPPH.

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ABSTRACT
Background: It was assumed that there might be association between serum zinclevel and executive function in children with ADHD. This study aimed to identifymean differences between serum zinc in ADHD children with executivedysfunction, without executive dysfunction, and non ADHD children, and to findcorrelation between serum zinc level and executive function in children withADHD.Method. This was a cross-sectional study with control group. Ninety childrenfrom two elementary schools in Jakarta were randomly selected as researchsubjects. They were categorized into ADHD children with executive dysfunction(n=30), ADHD children without executive dysfunction (n=30), and non ADHDchildren (n=30). Serum zinc was analyzed using Inductively Coupled Plasma-Mass Spectrophotometry method. Executive function was examined usingBRIEF-Indonesian version. Data was analyzed using SPSS 20 for Windows.Result. Seventy five percent of research subjects experinced zinc deficiency.Meanwhile, 60% of children with ADHD suffered from zinc deficiency. Therewas no significant difference in mean serum zinc between ADHD children withexecutive dysfunction, without executive dysfunction, and non ADHD children(59.40 g/dL vs. 55.36 g/dL vs. 52.93 g/dL, p=0.119). The coefficientcorrelation between serum zinc level and executive function in ADHD childrenwas 0,128.Conclusion. Serum zinc level might not associate directly with executivedysfunction, however it might link with clinical symptoms of ADHD. Furtherstudy needs to be done in order to obtain a more clear understanding of serumzinc and executive function in children with ADHD, Background. It was assumed that there might be association between serum zinclevel and executive function in children with ADHD. This study aimed to identifymean differences between serum zinc in ADHD children with executivedysfunction, without executive dysfunction, and non ADHD children, and to findcorrelation between serum zinc level and executive function in children withADHD.Method. This was a cross-sectional study with control group. Ninety childrenfrom two elementary schools in Jakarta were randomly selected as researchsubjects. They were categorized into ADHD children with executive dysfunction(n=30), ADHD children without executive dysfunction (n=30), and non ADHDchildren (n=30). Serum zinc was analyzed using Inductively Coupled Plasma-Mass Spectrophotometry method. Executive function was examined usingBRIEF-Indonesian version. Data was analyzed using SPSS 20 for Windows.Result. Seventy five percent of research subjects experinced zinc deficiency.Meanwhile, 60% of children with ADHD suffered from zinc deficiency. Therewas no significant difference in mean serum zinc between ADHD children withexecutive dysfunction, without executive dysfunction, and non ADHD children(59.40 g/dL vs. 55.36 g/dL vs. 52.93 g/dL, p=0.119). The coefficientcorrelation between serum zinc level and executive function in ADHD childrenwas 0,128.Conclusion. Serum zinc level might not associate directly with executivedysfunction, however it might link with clinical symptoms of ADHD. Furtherstudy needs to be done in order to obtain a more clear understanding of serumzinc and executive function in children with ADHD]