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ABSTRAKProporsi kematian karena MDR TB di Rumah Sakit Hasan Sadikin Bandung
12,73%. Penelitian ini bertujuan untuk melihat factor factor yang mempengaruhi
ketahanan hidup pasien MDR TB di Rumah Sakit Hasan Sadikin Bandung.
Desain penelitian yang digunakan adalah kohort retrospektif dengan jumlah
sampel 216 di mana 80 sebagai event dan sisanya sebagai sensor. Hasil analisis
dengan Survival dengan Spss memperlihatkan predictor utama dari ketahanan
hidup pasien MDR TB di RSHS adalah pola resistensi(HR 0,3 ; 95% CI 0,2-0,5; P
value 0,000), efek samping obat berhubungan dengan waktu(HR 1,12; 95% CI
1,02-1,22; P value 0,013)dan BMI kurang (HR 1,8; 95%CI 1,02-3,3; P value
0,04). Efek samping obat sebelum terapi bulan kedelapan efeknya proteksi,
sedangkan sesudah itu meningkatkan resiko kematian. Konfoundingnya adalah
riwayat merokok, jenis kelamin, umur dan pekerjaan. Probabilitas ketahanan
hidup pasien MDR TB 0,56. Oleh sebab itu peningkatan kepatuhan minum obat,
konsistennya pengukuran tinggi badan dan berat badan pasien MDR TB dan
efektivitas manajemen efek samping OAT dapat meningkatkan ketahanan hidup
pasien MDR TB di Rumah Sakit Hasan Sadikin Bandung.
ABSTRACTProportion death caused by MDR TB at Hasan Sadikin General Hospital in
Bandung (RSHS) is 12,73%. This study is observe factors affecting the survival of
patient with MDR TB at Hasan Sadikin General Hospital Bandung. The study
design uses retrospective cohorts with sample size 216 patient, whereas 80 of
them is used as event and the rest is treated as sensor. Survival analysis results
using SPSS demonstrated main predictors of survival among MDR TB patient in
RSHS, which are : resistancy pattern (HR 0,31; 95%CI 0,2-0,5; P value 0,000),
drug side effect with time dependent (HR 1,12; 95%CI 1,02-1,22; P value 0,013),
and BMI (HR 1,8; 95% CI 0,2-3,3, P value 0,04). Confounding factors found was
smoking history, sex/gender, age and occupation. The propability of MDR TB
patient?survival is 0,56. Therefore improving drug taking compliance, consistant
monitoring and improvement of BMI as well as management of anti TB drug side
effect may improve the survival of MDR TB patient at Hasan Sadikin General
Hospital in Bandung.;Proportion death caused by MDR TB at Hasan Sadikin General Hospital in
Bandung (RSHS) is 12,73%. This study is observe factors affecting the survival of
patient with MDR TB at Hasan Sadikin General Hospital Bandung. The study
design uses retrospective cohorts with sample size 216 patient, whereas 80 of
them is used as event and the rest is treated as sensor. Survival analysis results
using SPSS demonstrated main predictors of survival among MDR TB patient in
RSHS, which are : resistancy pattern (HR 0,31; 95%CI 0,2-0,5; P value 0,000),
drug side effect with time dependent (HR 1,12; 95%CI 1,02-1,22; P value 0,013),
and BMI (HR 1,8; 95% CI 0,2-3,3, P value 0,04). Confounding factors found was
smoking history, sex/gender, age and occupation. The propability of MDR TB
patient?survival is 0,56. Therefore improving drug taking compliance, consistant
monitoring and improvement of BMI as well as management of anti TB drug side
effect may improve the survival of MDR TB patient at Hasan Sadikin General
Hospital in Bandung., Proportion death caused by MDR TB at Hasan Sadikin General Hospital in
Bandung (RSHS) is 12,73%. This study is observe factors affecting the survival of
patient with MDR TB at Hasan Sadikin General Hospital Bandung. The study
design uses retrospective cohorts with sample size 216 patient, whereas 80 of
them is used as event and the rest is treated as sensor. Survival analysis results
using SPSS demonstrated main predictors of survival among MDR TB patient in
RSHS, which are : resistancy pattern (HR 0,31; 95%CI 0,2-0,5; P value 0,000),
drug side effect with time dependent (HR 1,12; 95%CI 1,02-1,22; P value 0,013),
and BMI (HR 1,8; 95% CI 0,2-3,3, P value 0,04). Confounding factors found was
smoking history, sex/gender, age and occupation. The propability of MDR TB
patient’survival is 0,56. Therefore improving drug taking compliance, consistant
monitoring and improvement of BMI as well as management of anti TB drug side
effect may improve the survival of MDR TB patient at Hasan Sadikin General
Hospital in Bandung.]
T43628-Ester Suryawati.pdf :: Unduh