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ABSTRAKPendahuluan: Menurut World Health Organization, populasi orang dengan
skizofrenia (ODS) di dunia adalah tujuh dari 1000 orang. Kelly (2002)
menyatakan bahwa 25% dari total 138 ODS mengalami gangguan fungsi
eksekutif. Pada metaanalisis Green (1996) dinyatakan bahwa fungsi eksekutif
dapat memengaruhi performa fungsi. Telah ada penelitian Desmiarti (2010) yang
meneliti hubungan antara defisit fungsi memori verbal dengan performa fungsi
ODS. Namun belum ada penelitian yang meneliti hubungan antara fungsi
eksekutif dengan performa fungsi ODS di Indonesia.
Metode: Penelitian menggunakan rancangan potong lintang pada 160 ODS di
Poliklinik Jiwa Dewasa RSUPN Dr. Cipto Mangunkusumo Jakarta. Penelitian ini
menggunakan instrumen Structured Clinical Interview For the DSM-IV Axis I
Disorders, Positive and Negative Symptoms Scale Excitement Components,
Extrapyramidal Syndrome Rating Scale, tes kemampuan membaca, Trail Making
Test (TMT) A dan B, Personal and Social Performance Scale (PSP).
Hasil: Pada penelitian ini didapatkan adanya hubungan bermakna antara fungsi
eksekutif (TMT B) dengan performa fungsi (PSP) yaitu p=0.014 dengan hasil
analisis korelasi Spearman p=0.000 dan koefisien korelasi r=-0.345. Pada hasil
analisis multivariat didapatkan adanya hubungan bermakna antara pendidikan
(OR=0.294, p=0.016), gejala penyakit (OR=0.271, p=0.006), status pernikahan
(OR=0.166, p=0.002), pekerjaan (OR=0.079, p=0.000), jenis antipsikotika
(OR=0.067, p=0.001) dengan performa fungsi (PSP).
Simpulan: Semakin tinggi skor TMT B (fungsi eksekutif) maka semakin rendah
skor PSP (performa fungsi) ODS. Defisit fungsi eksekutif (TMT B) berhubungan
langsung dengan performa fungsi (PSP). Faktor yang juga berpengaruh pada
performa fungsi (PSP) adalah pendidikan, gejala penyakit, status pernikahan,
pekerjaan dan jenis antipsikotika. Instrumen TMT B dapat lebih spesifik menilai
fungsi eksekutif pada kelompok ODS sehingga dapat digunakan sebagai alat
deteksi defisit fungsi kognitif di layanan psikiatri.
ABSTRACTIntroduction: Based on World Health Organization, schizophrenia population in
the world is seven from 1000. Kelly (2002) said that 25% from 138 schizophrenia
people experiencing executive function disorder. Green metaanalysis (1996)
stated that executive function can influence function performance. There is a
Desmiarti?s research (2010) that examine relationship between verbal memory
function deficit with function performance in schizophrenia. However, there is no
research that examine relationship between executive function with function
performance in schizophrenia at Indonesia.
Method: This research using cross-sectional design from 160 schizophrenia
people at Poliklinik Jiwa Dewasa RSUPN Dr. Cipto Mangunkusumo Jakarta. This
research using instrument such as Structured Clinical Interview For the DSM-IV
Axis I Disorders, Positive and Negative Symptoms Scale Excitement
Components, Extrapyramidal Syndrome Rating Scale, reading ability test, Trail
Making Test (TMT) A and B, Personal and Social Performance Scale (PSP).
Result: There is a significant relationship in this research between executive
function (TMT B) with function performance (PSP) p=0.014 by Spearman
correlation analysis result p=0.000 and correlation coefficient r=-0.345. There are
significant relationship in this research multivariate analysis between education
(OR=0.294, p=0.016), schizophrenia symptoms (OR=0.271, p=0.006), married
status (OR=0.166, p=0.002), job (OR=0.079, p=0.000), antipsychotics
(OR=0.067, p=0.001) with function performance (PSP).
Conclusion: The higher TMT B score (executive function), the lower PSP score
(function performance) of schizophrenia people. Executive function deficit (TMT
B) have a direct relation with function performance (PSP). Another factors that
have influence to function performance (PSP) are education, schizophrenia
symptoms, married status, job, antipsychotics. TMT B instrumen was more
specific to assess executive function at schizophrenia group so TMT B can be
used as detection tool of cognitive function deficit on psychiatric care, Introduction: Based on World Health Organization, schizophrenia population in
the world is seven from 1000. Kelly (2002) said that 25% from 138 schizophrenia
people experiencing executive function disorder. Green metaanalysis (1996)
stated that executive function can influence function performance. There is a
Desmiarti’s research (2010) that examine relationship between verbal memory
function deficit with function performance in schizophrenia. However, there is no
research that examine relationship between executive function with function
performance in schizophrenia at Indonesia.
Method: This research using cross-sectional design from 160 schizophrenia
people at Poliklinik Jiwa Dewasa RSUPN Dr. Cipto Mangunkusumo Jakarta. This
research using instrument such as Structured Clinical Interview For the DSM-IV
Axis I Disorders, Positive and Negative Symptoms Scale Excitement
Components, Extrapyramidal Syndrome Rating Scale, reading ability test, Trail
Making Test (TMT) A and B, Personal and Social Performance Scale (PSP).
Result: There is a significant relationship in this research between executive
function (TMT B) with function performance (PSP) p=0.014 by Spearman
correlation analysis result p=0.000 and correlation coefficient r=-0.345. There are
significant relationship in this research multivariate analysis between education
(OR=0.294, p=0.016), schizophrenia symptoms (OR=0.271, p=0.006), married
status (OR=0.166, p=0.002), job (OR=0.079, p=0.000), antipsychotics
(OR=0.067, p=0.001) with function performance (PSP).
Conclusion: The higher TMT B score (executive function), the lower PSP score
(function performance) of schizophrenia people. Executive function deficit (TMT
B) have a direct relation with function performance (PSP). Another factors that
have influence to function performance (PSP) are education, schizophrenia
symptoms, married status, job, antipsychotics. TMT B instrumen was more
specific to assess executive function at schizophrenia group so TMT B can be
used as detection tool of cognitive function deficit on psychiatric care]