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Endoplasmic reticulum stress in health and disease

edited by Patrizia Agostinis, Afshin Samali (Springer, 2012)

 Abstrak

This book primarily focuses on the pathophysiology of ER stress. It introduces the molecular bases of ER stress, the emerging relevance of the ER-mitochondria cross-talk, the signaling pathways engaged and cellular responses to ER stress, including the adaptive Unfolded Protein Response (UPR), autophagy as well as cell death. Next the book addresses the role of ER stress in physiology and in the etiology of relevant pathological conditions, like carcinogenesis and inflammation, neurodegeneration and metabolic disease. The last chapter describes how ER stress pathways can be targeted for therapeutic benefit. Altogether, this book will provide the reader with an exhaustive view of ER stress biology and the latest insights in the role of ER stress in relevant human diseases.

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 Metadata

Jenis Koleksi : eBooks
No. Panggil : e20417396
Entri tambahan-Nama orang :
Subjek :
Penerbitan : Dordrecht: Springer, 2012
Sumber Pengatalogan: LibUI eng rda
Tipe Konten: text
Tipe Media: computer
Tipe Pembawa: online resource
Deskripsi Fisik:
Tautan: http://link.springer.com/book/10.1007%2F978-94-007-4351-9
Lembaga Pemilik:
Lokasi:
  • Ketersediaan
  • Ulasan
  • Sampul
No. Panggil No. Barkod Ketersediaan
e20417396 20-22-34006457 TERSEDIA
Ulasan:
Tidak ada ulasan pada koleksi ini: 20417396
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