eBooks :: Kembali

eBooks :: Kembali

Phosphoinositides I: enzymes of synthesis and degradation

Tamas Balla, Matthias Wymann, John D.York ([Springer, ], 2012)

 Abstrak

In two volumes, this book elucidates the crucial mechanisms that control the dynamics of phosphoinositide conversion. Starting out from phosphatidylinositol, a chain of lipid kinases collaborates to generate the oncogenic lipid phosphatidylinositol(3,4,5)-trisphosphate. For every phosphate group added, there are specific lipid kinases – and phosphatases to remove it. Additionally, phospholipases can cleave off the inositol head group and generate poly-phosphoinositols, which act as soluble signals in the cytosol. Volume I untangles the web of these enzymes and their products, and relates them to function in health and disease. Phosphoinositide 3-kinases and 3-phosphatases have received a special focus in volume I, and recent therapeutic developments in human disease are presented along with a historical perspective illustrating the impressive progress in the field.

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Jenis Koleksi : eBooks
No. Panggil : e20417501
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Subjek :
Penerbitan : Dordrecht: [Springer, ], 2012
Sumber Pengatalogan: LibUI eng rda
Tipe Konten: text
Tipe Media: computer
Tipe Pembawa: online resource
Deskripsi Fisik:
Tautan: http://link.springer.com/book/10.1007%2F978-94-007-3012-0
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