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UI - Skripsi Membership :: Kembali

Distribusi pola polimorfisme leptin G-2548A pada pasien dengan dan tanpa osteoporosis = Pattern distribution polymorphism leptin G-2548A in human with and without osteoporosis

Yossi Nurul Utami Damayanti; Agoeng Tjahajani Sarwono, supervisor; Elza Ibrahim, supervisor; Mindya Yuniastuti, examiner; Hedijanti Joenoes, examiner (Fakultas Kedokteran Gigi Universitas Indonesia, 2016)

 Abstrak

[ABSTRAK
Penelitian ini bertujuan untuk menganalisis distribusi pola polimorfisme gen LEP
G-2548A pada pasien dengan dan tanpa osteoporosis. Seratus sampel terdiri dari
pasien dengan osteoporosis (50 sampel) dan pasien tanpa osteoporosis (50
sampel). Polimorfisme gen LEP G-2548A dianalisis menggunakan metode PCRRFLP.
Perhitungan distribusi genotip dan alel pada kedua kelompok
menggunakan uji Fisher. Frekuensi alel A dan genotip AA gen LEP G-2548A
pada pasien osteoporosis berisiko meningkat dibandingkan pada pasien tanpa
osteoporosis. Genotip LEP G-2548A pada pasien dengan dan tanpa osteoporosis
memiliki hubungan tidak berbeda bermakna (p = 0,191). Distribusi pola
polimorfisme gen LEP G-2548A berisiko meningkat pada pasien dengan
osteoporosis
ABSTRACT
The aim of this study was to analyzed pattern distribution polymorphism LEP G-
2548A in patient with and without osteoporosis.One hundred samples consist of
patient with and without osteoporosis.Genetic polymorhism LEP G-2548A were
analyzed by PCR-RFLP methods.The calculation of the distribution of genotypes
and alleles in both groups using Fisher test.The frequency of A allele and AA
genotype LEP G-2548A gene presented increased risk in patient with
osteoporosis.Statistical analysis of LEP G-2548A gene using fisher test between
patient with and without osteoporosis showed no significant differences
(p=0,191).Distribution of leptin gene G-2548A polymorphism pattern presented
increased risk in patient with osteoporosis;The aim of this study was to analyzed pattern distribution polymorphism LEP G-
2548A in patient with and without osteoporosis.One hundred samples consist of
patient with and without osteoporosis.Genetic polymorhism LEP G-2548A were
analyzed by PCR-RFLP methods.The calculation of the distribution of genotypes
and alleles in both groups using Fisher test.The frequency of A allele and AA
genotype LEP G-2548A gene presented increased risk in patient with
osteoporosis.Statistical analysis of LEP G-2548A gene using fisher test between
patient with and without osteoporosis showed no significant differences
(p=0,191).Distribution of leptin gene G-2548A polymorphism pattern presented
increased risk in patient with osteoporosis, The aim of this study was to analyzed pattern distribution polymorphism LEP G-
2548A in patient with and without osteoporosis.One hundred samples consist of
patient with and without osteoporosis.Genetic polymorhism LEP G-2548A were
analyzed by PCR-RFLP methods.The calculation of the distribution of genotypes
and alleles in both groups using Fisher test.The frequency of A allele and AA
genotype LEP G-2548A gene presented increased risk in patient with
osteoporosis.Statistical analysis of LEP G-2548A gene using fisher test between
patient with and without osteoporosis showed no significant differences
(p=0,191).Distribution of leptin gene G-2548A polymorphism pattern presented
increased risk in patient with osteoporosis]

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 Metadata

Jenis Koleksi : UI - Skripsi Membership
No. Panggil : S-Pdf
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Entri tambahan-Nama badan :
Program Studi :
Subjek :
Penerbitan : [Place of publication not identified]: Fakultas Kedokteran Gigi Universitas Indonesia, 2016
Bahasa : ind
Sumber Pengatalogan : LibUI ind rda
Tipe Konten : text
Tipe Media : computer
Tipe Carrier : online resource
Deskripsi Fisik : xv, 55 pages : illustration ; 28 cm + Appendix
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 3
  • Ketersediaan
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No. Panggil No. Barkod Ketersediaan
S-Pdf 14-17-230031721 TERSEDIA
Ulasan:
Tidak ada ulasan pada koleksi ini: 20421488
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