UI - Tugas Akhir :: Kembali

UI - Tugas Akhir :: Kembali

Hubungan pajanan partikulat debu terhadap kejadian rinitis akibat kerja dengan biomarker eosinofil kerokan mukosa hidung pada pekerja di area parkir basement = Association of particulate dust exposure with the incidence of occupational rhinitis using eosinophils nasal mucosal scrapings as biomarker among basement parking area workers

Rina Metalapa; Niken Lestari, supervisor; Setyawati Budiningsih, supervisor (Fakultas Kedokteran Universitas Indonesia, 2015)

 Abstrak

ABSTRAK
Prevalensi Rinitis Akibat Kerja (RAK) berkisar antara 5-48%. Penyebab RAK
antara lain adalah partikulat debu yang beterbangan di lingkungan kerja. Hal ini
akan meningkatkan beban pembiayaan baik terhadap pekerja itu sendiri maupun
perusahaan tempat ia bekerja. Penelitian ini bertujuan untuk mengetahui
prevalensi RAK serta hubungan antara kadar partikulat debu dengan kejadian
RAK dengan populasi pekerja parkir basement di sebuah Hotel dan RSUD di
Jakarta dengan waktu pengumpulan sampel dilakukan selama bulan Desember
2014 hingga Maret 2015. Sampel penelitian adalah yang memenuhi kriteria
inklusi yakni area kerja di parkir basement, usia 20-40 tahun, masa kerja lebih
dari 1 tahun dan bersedia mengikuti prosedur penelitian. Subyek penelitian di
wawancara dan diperiksa kadar eosinofil kerokan mukosa hidung sebelum dan
sesudah bekerja. RAK positif apabila terdapat gejala rinitis, memberat ketika
bekerja dan ada peningkatan eosinofil kerokan mukosa hidung. Analisa penelitian
dilakukan berdasarkan karakteristik usia, jenis kelamin, masa kerja, kebiasaan
merokok dan bagian kerja (terpapar langsung atau tidak dengan partikulat debu).
Dari 57 subyek penelitian, 6 orang (10.5%) mengalami peningkatan eosinofil
dengan karakterisktik sebagai berikut: 4 orang memiliki masa kerja > 4 tahun; 4
orang memiliki kebiasaan merokok; dan 3 orang bekerja di bagian kerja yang
terpapar langsung dengan partikulat debu. Dari 6 orang tersebut terdapat 3 orang
(5.2%) yang memenuhi kriteria RAK dengan karakteristik sebagai berikut: 2
orang berusia 30-40 tahun, 2 orang adalah laki-laki, 2 orang mempunyai masa
kerja ≤ 4 tahun, dan 2 orang berasal dari bagian kerja yang terpapar tidak
langsung dengan partikulat debu. Terdapat hubungan bermakna antara riwayat
atopi dengan peningkatan eosinofil (OR 23.33 dan 95%CI 2.40-224.62). Namun
tidak ditemukan hubungan antara kadar partikulat debu dan masa kerja dengan RAK yang bermakna.
ABSTRACT
The prevalence of occupational rhinitis ranges between 5-48%. It is caused by
particulate dust in the workplace. It will increase financial burden both for the
workers themselves and the company. This study aims to determine the
prevalence of OR and the relation between the levels of particulate dust with OR
incident among workers who work in a hotel or hospital basement parking lot in
Jakarta, during December 2014 to March 2015. The sample inclusion criteria
were: age 20-40 years, working period of more than one year and are willing to
participate in the study. The subjects were interviewed and nasal mucosal
scrapings eosinophil levels were measured before and after work. OR was
defined as has symptoms of rhinitis, increase during work and there is an
increase in eosinophils nasal mucosal scrapings. Analysis of the research carried
out based on the characteristics of age, sex, years of smoking and working
directly or indirectly exposed to dust particulates. Of the 57 subjects of the study,
6 (10.5%) experienced an increase in eosinophils with the following
characteristics: 4 people has a work period > 4 years; 4 people smoke; and 3
people work directly exposed to particulate dust. Three subjects (5.2%) meet all
the OR criteria with the following characteristics: 2 were aged 30-40 years, 2
were male, 2 have a working period of ≤ 4 years and 2 were indirectly exposed to
particulate dust. There is a very significant association between history of atopy
with increased eosinophils (, OR 23.3 and 95% CI 2.40-224.62). However, no association was found between levels of particulate dust and working period.;The prevalence of occupational rhinitis ranges between 5-48%. It is caused by
particulate dust in the workplace. It will increase financial burden both for the
workers themselves and the company. This study aims to determine the
prevalence of OR and the relation between the levels of particulate dust with OR
incident among workers who work in a hotel or hospital basement parking lot in
Jakarta, during December 2014 to March 2015. The sample inclusion criteria
were: age 20-40 years, working period of more than one year and are willing to
participate in the study. The subjects were interviewed and nasal mucosal
scrapings eosinophil levels were measured before and after work. OR was
defined as has symptoms of rhinitis, increase during work and there is an
increase in eosinophils nasal mucosal scrapings. Analysis of the research carried
out based on the characteristics of age, sex, years of smoking and working
directly or indirectly exposed to dust particulates. Of the 57 subjects of the study,
6 (10.5%) experienced an increase in eosinophils with the following
characteristics: 4 people has a work period > 4 years; 4 people smoke; and 3
people work directly exposed to particulate dust. Three subjects (5.2%) meet all
the OR criteria with the following characteristics: 2 were aged 30-40 years, 2
were male, 2 have a working period of ≤ 4 years and 2 were indirectly exposed to
particulate dust. There is a very significant association between history of atopy
with increased eosinophils (, OR 23.3 and 95% CI 2.40-224.62). However, no association was found between levels of particulate dust and working period.;The prevalence of occupational rhinitis ranges between 5-48%. It is caused by
particulate dust in the workplace. It will increase financial burden both for the
workers themselves and the company. This study aims to determine the
prevalence of OR and the relation between the levels of particulate dust with OR
incident among workers who work in a hotel or hospital basement parking lot in
Jakarta, during December 2014 to March 2015. The sample inclusion criteria
were: age 20-40 years, working period of more than one year and are willing to
participate in the study. The subjects were interviewed and nasal mucosal
scrapings eosinophil levels were measured before and after work. OR was
defined as has symptoms of rhinitis, increase during work and there is an
increase in eosinophils nasal mucosal scrapings. Analysis of the research carried
out based on the characteristics of age, sex, years of smoking and working
directly or indirectly exposed to dust particulates. Of the 57 subjects of the study,
6 (10.5%) experienced an increase in eosinophils with the following
characteristics: 4 people has a work period > 4 years; 4 people smoke; and 3
people work directly exposed to particulate dust. Three subjects (5.2%) meet all
the OR criteria with the following characteristics: 2 were aged 30-40 years, 2
were male, 2 have a working period of ≤ 4 years and 2 were indirectly exposed to
particulate dust. There is a very significant association between history of atopy
with increased eosinophils (, OR 23.3 and 95% CI 2.40-224.62). However, no association was found between levels of particulate dust and working period.;The prevalence of occupational rhinitis ranges between 5-48%. It is caused by
particulate dust in the workplace. It will increase financial burden both for the
workers themselves and the company. This study aims to determine the
prevalence of OR and the relation between the levels of particulate dust with OR
incident among workers who work in a hotel or hospital basement parking lot in
Jakarta, during December 2014 to March 2015. The sample inclusion criteria
were: age 20-40 years, working period of more than one year and are willing to
participate in the study. The subjects were interviewed and nasal mucosal
scrapings eosinophil levels were measured before and after work. OR was
defined as has symptoms of rhinitis, increase during work and there is an
increase in eosinophils nasal mucosal scrapings. Analysis of the research carried
out based on the characteristics of age, sex, years of smoking and working
directly or indirectly exposed to dust particulates. Of the 57 subjects of the study,
6 (10.5%) experienced an increase in eosinophils with the following
characteristics: 4 people has a work period > 4 years; 4 people smoke; and 3
people work directly exposed to particulate dust. Three subjects (5.2%) meet all
the OR criteria with the following characteristics: 2 were aged 30-40 years, 2
were male, 2 have a working period of ≤ 4 years and 2 were indirectly exposed to
particulate dust. There is a very significant association between history of atopy
with increased eosinophils (, OR 23.3 and 95% CI 2.40-224.62). However, no association was found between levels of particulate dust and working period.

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 Metadata

Jenis Koleksi : UI - Tugas Akhir
No. Panggil : SP-PDF
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Entri tambahan-Nama badan :
Program Studi :
Subjek :
Penerbitan : [Place of publication not identified]: Fakultas Kedokteran Universitas Indonesia, 2015
Bahasa : ind
Sumber Pengatalogan : LibUI ind rda
Tipe Konten : text
Tipe Media : computer
Tipe Carrier : online resource
Deskripsi Fisik : xv, 82 pages : illustration + appendix
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 3
  • Ketersediaan
  • Ulasan
  • Sampul
No. Panggil No. Barkod Ketersediaan
SP-PDF 16-18-583095908 TERSEDIA
Ulasan:
Tidak ada ulasan pada koleksi ini: 20424582
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