UI - Tugas Akhir :: Kembali

UI - Tugas Akhir :: Kembali

Akurasi pemeriksaan dahak BTA dibandingkan dengan biakan M. Tuberculosis pada pasien terduga TB paru = Accuracy of sputum smear compared with culture in patients with Tuberculosis suspect

Ery Irawan; Erlina Burhan, supervisor; Moh. Arifin Nawas, supervisor (Fakultas Kedokteran Universitas Indonesia, 2015)

 Abstrak

ABSTRAK
Latar Belakang: dahak BTA mikroskopik adalah teknik diagnostik cepat yang paling
banyak digunakan untuk mendiagnosis TB paru. Di RSUP Persahabatan, pemeriksaan
dahak BTA mikroskopik membutuhkan tiga pemeriksaan sampel dahak lebih dari dua
hari, (sewaktu pertama, pagi, sewaktu kedua). Pengambilan dua sampel dahak akan
mengurangi waktu, uang dan beban kerja laboratorium mikrobiologi
Tujuan: Penelitian ini bertujuan untuk mendapatkan sensitivitas dan spesifisitas
pemeriksaan dahak BTA mikroskopik dari tiga bahan pemeriksaan dahak dan dua
bahan pemeriksaan dahak.
Metode: Kami secara acak mengumpulkan data demografi dan hasil laboratorium (hasil
dahak BTA dan hasil biakan M.tuberculosis) dari pasien terduga TB kasus baru di RSUP
Persahabatan dari data bulan Januari 2012 hingga Desember 2013. Subjek harus berusia
minimal 15 tahun dan bukan pasien TB MDR dan bukan pasien HIV
Hasil: Dari 360 pasien terduga TB paru, sebanyak 210/360 (58,3%) memiliki hasil
biakan M. tuberculosis positif. Sensitivitas 100% dan spesifisitas 69.2% pada hasil
pemeriksaan BTA mikroskopik tiga kali (S1, P, S2) dan hasil pemeriksaan BTA
mikroskopik dua kali sensitivitasnya 89.8% dan spesifisitas 94.1%.
Kesimpulan: Hasil pemeriksaan dahak BTA mikroskopik 2 kali pemeriksaan
memberikan spesifisitas yang lebih tinggi bila dibandingkan dengan hasil pemeriksaan
3 kali dahak BTA mikroskopik dan memiliki sensitivitas yang masih cukup tinggi.
ABSTRACT
Background: Sputum smear microscopy is the rapid diagnostic technique that most
widely used for diagnosing pulmonary tuberculosis. In Persahabatan hospital, sputum
smear microscopy requires three sputum sample examinations over two days, (spot1,
morning, spot2). Collection of two sputum samples would reduce time, money and
work load of microbiology laboratory.
Objectives: This study aimed to get sensitivity and specificity of sputum smear
microscopy from three sputum samples collection and two sputum samples collection.
Methods: We randomly collected demography and laboratory data (sputum smear and
M.tuberculosis culture result) of presumptive TB new cases in Persahabatan hospital
from January 2012 to Desember 2013. Subjects must be 15 years old minimum, non
multidrug-resistant TB presumptive and have non reactive HIV status.
Results: Of 360 presumptive TB patients, 58.3% have M.tuberculosis positive culture
results. Senstivity and specificity of sputum smear microscopy from three sputum
samples collection (S1, M, S2) are 100% and 69.2%. Smear microscopy of two samples
collection Sensitivity and specificity sputum smear microscopy 89.8% and 94.1%.
Conclusion: Sputum smear microscopy test result from 2 sputum collections gives
increase specificity compared to smear microscopy of 3 samples and have highly sensitivity.
;Background: Sputum smear microscopy is the rapid diagnostic technique that most
widely used for diagnosing pulmonary tuberculosis. In Persahabatan hospital, sputum
smear microscopy requires three sputum sample examinations over two days, (spot1,
morning, spot2). Collection of two sputum samples would reduce time, money and
work load of microbiology laboratory.
Objectives: This study aimed to get sensitivity and specificity of sputum smear
microscopy from three sputum samples collection and two sputum samples collection.
Methods: We randomly collected demography and laboratory data (sputum smear and
M.tuberculosis culture result) of presumptive TB new cases in Persahabatan hospital
from January 2012 to Desember 2013. Subjects must be 15 years old minimum, non
multidrug-resistant TB presumptive and have non reactive HIV status.
Results: Of 360 presumptive TB patients, 58.3% have M.tuberculosis positive culture
results. Senstivity and specificity of sputum smear microscopy from three sputum
samples collection (S1, M, S2) are 100% and 69.2%. Smear microscopy of two samples
collection Sensitivity and specificity sputum smear microscopy 89.8% and 94.1%.
Conclusion: Sputum smear microscopy test result from 2 sputum collections gives
increase specificity compared to smear microscopy of 3 samples and have highly sensitivity.
;Background: Sputum smear microscopy is the rapid diagnostic technique that most
widely used for diagnosing pulmonary tuberculosis. In Persahabatan hospital, sputum
smear microscopy requires three sputum sample examinations over two days, (spot1,
morning, spot2). Collection of two sputum samples would reduce time, money and
work load of microbiology laboratory.
Objectives: This study aimed to get sensitivity and specificity of sputum smear
microscopy from three sputum samples collection and two sputum samples collection.
Methods: We randomly collected demography and laboratory data (sputum smear and
M.tuberculosis culture result) of presumptive TB new cases in Persahabatan hospital
from January 2012 to Desember 2013. Subjects must be 15 years old minimum, non
multidrug-resistant TB presumptive and have non reactive HIV status.
Results: Of 360 presumptive TB patients, 58.3% have M.tuberculosis positive culture
results. Senstivity and specificity of sputum smear microscopy from three sputum
samples collection (S1, M, S2) are 100% and 69.2%. Smear microscopy of two samples
collection Sensitivity and specificity sputum smear microscopy 89.8% and 94.1%.
Conclusion: Sputum smear microscopy test result from 2 sputum collections gives
increase specificity compared to smear microscopy of 3 samples and have highly sensitivity.

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Jenis Koleksi : UI - Tugas Akhir
No. Panggil : SP-PDF
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Entri tambahan-Nama badan :
Program Studi :
Subjek :
Penerbitan : [Place of publication not identified]: Fakultas Kedokteran Universitas Indonesia, 2015
Bahasa : ind
Sumber Pengatalogan : LibUI ind rda
Tipe Konten : text
Tipe Media : computer
Tipe Carrier : online resource
Deskripsi Fisik : xv, 56 pages : illustration + appendix
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 3
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No. Panggil No. Barkod Ketersediaan
SP-PDF 16-18-704530840 TERSEDIA
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Tidak ada ulasan pada koleksi ini: 20424614
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