The article discuses the actors and leaders in the business world in the perspective of ethics on responsibility. The economy and business are market by two kinds of realities, global capitalism and adoration to the market systems, and free trade. Karl Marx said that capital is the religion of a modern society which looses its God. If fact, business has become one of the causes of the gap between the rich and poor, damage on the environment, and consumptive behavior. When businesses are enhanced without a sense of responsibility, a global disaster will arise.