The paper examines the interaction of fiscal and monetary policy and the effectiveness of Inflaction Targetting Framework (ITF) using vector Autoregression (VAR) method in Indonesia from 2000 to 2013. The study uses model that is estimated from the Nordhaus approach and the secondary data obtained from Federal Reserve St.Lois (FRED) and CEIC. The study shows the absence of fiscal dominance in Indonesia and the ITF is moderately effective in achieving targeted inflation rate. Tightening monetary policy by bank Indonesia is able to affect almost 30 per-cent the change in inflation variability after two year. Expansionary fiscal policy is only able to reduce the unemployment in a very short term, which will potentially lead to inflation. The results suggest that in a short term the coordination of fiscal and monetary policy is needed and effective to archieve lower unemployment and minimize the gap between the targeted and actual inflation .