ABSTRAK
Latar Belakang: Periodontitis merupakan faktor risiko terjadinya PenyakitJantung Koroner (PJK). Interleukin-1β merupakan sitokin pro-inflamasi utamayang dapat ditemukan pada kedua penyakit ini.Tujuan: Menganalisis hubungankadar interleukin-1β dalam cairan sulkus gingiva (CSG) penderita PJK dan nonPJK dengan status periodontal. Metode: Pemeriksaan klinis 40 subjek PJK dan40 subjek non PJK, pemeriksaan laboratorium kadar Interleukin-1β dengan ELISA.Hasil : Tidak terdapat perbedaan bermakna Interleukin-1β antara penderita PJK dannon PJK (p>0,05); tidak terdapat perbedaan bermakna antara kadar Interleukin-1βdengan status periodontal penderita PJK dan non- PJK (p>0,05). Kesimpulan: KadarInterleukin-1β penderita PJK tidak memiliki hubungan dengan status periodontal.Kata kunci : interleukin-1β, penyakit jantung koroner, status periodontal,cairan sulkus gingiva

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ABSTRACT
Background: Periodontitis is a risk factor for coronary heart disease. Interleukin-1β as a pro-inflammatory main cytokine, can be found in this both diseases.Objective: To analyze the relationship of interleukin-1β levels in CSG CHD andnon-CHD patients with periodontal status. Methods: Clinical Examination for 40Subject CHD and 40 controls was checked, laboratory test for measured the levelsof Interleukin-1β with ELISA. Results: There were no significant differencesbetween patients Interleukin-1β CHD and non-CHD (p>0.05); there is nosignificant difference between the levels of Interleukin-1β with periodontal statusCHD and control patients (p>0.05) Conclusions: Levels of Interleukin-1β ofCHD patients do not have a relationships with periodontal status.