ABSTRAKTB merupakan tantangan bagi pengendalian Acquired Immunodeficiency
Syndrome (AIDS) karena merupakan infeksi oportunistik terbanyak pada orang
dengan HIV/AIDS (ODHA). TB dapat meningkatkan progresivitas HIV dan
meningkatkan risiko kematian bagi penderita HIV. Tujuan penelitian ini adalah
untuk mengetahui prediktor yang berhubungan dengan kejadian TB pada ODHA
di RS dr. H. Marzoeki Mahdi Bogor Tahun 2014-2016. Desain studi yang
digunakan adalah cross sectional dengan menggunakan data register ART dan
Rekam Medis.Sampel berjumlah 817 pasien HIV. Analisis data dilakukan dengan
mengguunakan multiple cox regression. Hasil analisis multivariat menunjukkan
adanya peningkatan risiko TB pada kelompok dengan anemia (PR=1,60, 95% CI:
1,18-2,29) dibandingkan kelompok tanpa anemia, adanya status IO (PR=4,83,
95% CI: 2,30-10,61) dibandingkan kelompok tanpa IO, stadium HIV 3-4
(PR=6,38, 95% CI: 3,22-12,65) dibandingkan stadium HIV 1-2 dan kadar CD4
dengan nilai PR masing masing kategori: kadar 350-499 Vs ≥500 (PR=2,52, 95%
CI: 0,33-19,34), kadar 200-349 Vs ≥500 (PR=2,71, 95% CI: 0,36-20,23), kadar
<200 Vs ≥500 (PR=3,31, 95% CI: 0,45-24,37).Selain itu ditemukan adanya
interaksi antara variabel stadium HIV dan status IO.
ABSTRACTTB is a challenge for the control of Acquired Immunodeficiency Syndrome (AIDS)
because it is the most common opportunistic infection in people living with with
HIV (PLWH). TB increase HIV progressivity and increase the risk of death for
PLWH. The purpose of this study is to determine the predictors are associated
with TB among PLWH in RS dr. H. Marzoeki Mahdi Bogor, 2014-2016. Study
design was cross sectional using ART register data and Medical Record. Total
sample of 817 HIV patients were collected. Multiple cox regression analysis were
applied in this research. The results of multivariate analysis showed an increased
risk of TB in the group with anemia (PR = 1.60, 95% CI: 1.18-2.29) compared to
the group without anemia, group with IO (PR = 4,83, 95% CI: 2,30-10,61) than
those without IO, HIV stage 3-4 (PR = 6,38, 95% CI: 3,22-12,65) than HIV stage
1-2, and CD4 levels with PR for each category: levels of 350-499 vs ≥500 (PR =
2.52, 95% CI: 0.33-19.34), levels of 200-349 vs ≥500 (PR = 2.71, 95% CI: 0.36-
20.23), levels <200 vs ≥500 (PR = 3.31, 95% CI: 0.45-24.37). In addition, there
was an interaction between HIV stage and IO.
T48421-Ulya Qoulan Karima.pdf :: Unduh