UI - Makalah dan Kertas Kerja :: Kembali

UI - Makalah dan Kertas Kerja :: Kembali

P-4: Molecular Docking Several Xanthone Compounds from Garcinia mangostana Linn. To Plasmepsin (Poster Presentation) - The 3rd Gruber-Soedigdo Lecture 2010 : Molecular biotechnology in Medicine & Bioindustry 27-30 July 2010)

Arry Yanuar; Mochamad Rezza Zuchrian; Berna Elya ([Publisher not identified] , 2010)

 Abstrak

ABSTRACT
Plasmepsin is a prime enzyme in malarial parasite life cycle. Plasmepsins are worked in the hemoglobin degradation inside the food vacuole during the erythrocytic phase. The structures of this enzyme are available through crystallography and show that these structures have an active site which allows many of probabilities of ligand interactions. Xanthone, a compound of active polyphenolic from Garcinia mangastana Linn. and a Xanthone compound which is isolated from Garcinia mangastona Linn. show an inhibition activity to Plasmadium falciparum through the in vitro method. In this research, the molecular docking method is used to study about inhibiton activity of the enzyme. Molecular docking result of Xanthone analogues to plasmepsin shows that more than one hydrogen bond are involved in the inhibition process.

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Jenis Koleksi : UI - Makalah dan Kertas Kerja
No. Panggil : MK-Pdf
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Entri tambahan-Nama badan :
Program Studi :
Subjek :
Penerbitan : [Place of publication not identified]: [Publisher not identified], 2010
Bahasa : eng
Sumber Pengatalogan : LibUI eng rda
Tipe Konten : text
Tipe Media : computer
Tipe Carrier : online resource
Deskripsi Fisik : 5 pages
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 3
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No. Panggil No. Barkod Ketersediaan
MK-Pdf 10-17-445944043 TERSEDIA
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Tidak ada ulasan pada koleksi ini: 20461515
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