Artikel Jurnal :: Kembali

Artikel Jurnal :: Kembali

Asthma biomarkers: do they bring precision medicine closer to the clinic? / Ioana Agache, Liliana Rogozea

Ioana Agache; Liliana Rogozea (The Korean Academy of Asthma, Allergy and Clinical Immunology, 2017)

 Abstrak

ABSTRACT
Measurement of biomarkers has been incorporated within clinical research of asthma to characterize the population and to associate the disease with environmental and therapeutic effects. Regrettably, at present, there are no specific biomarkers, none is validated or qualified, and endotype driven choices overlap. Biomarkers have not yet reached clinical practice and are not included in current asthma guidelines. Last but not least, the choice of the outcome upholding the value of the biomarkers is extremely difficult, since it has to reflect the mechanistic intervention while being relevant to both the disease and the particular person. On the verge of a new age of asthma healthcare standard, we must embrace and adapt to the key drivers of change. Disease endotypes, biomarkers, and precision medicine represent an emerging model of patient care building on large scale biologic databases, omics and diverse cellular assays, health information technology, and computational tools for analyzing sizable sets of data. A profound transformation of clinical and research pattern from population to individual risk and from investigator imposed subjective disease clustering (hypothesis driven) to unbiased, data driven models is facilitated by the endotype biomarker driven approach.

 Metadata

Jenis Koleksi : Artikel Jurnal
No. Panggil : 610 AAIR 9:6 (2017)
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Subjek :
Penerbitan : Suwon: The Korean Academy of Asthma, Allergy and Clinical Immunology, 2017
Sumber Pengatalogan : LibUI eng rda
ISSN : 20927355
Majalah/Jurnal : Allergy, Asthma & Immunology Research
Volume : Vol. 9, No. 6, November 2017: 466-476
Tipe Konten : text
Tipe Media : unmediated
Tipe Carrier : volume
Akses Elektronik :
Institusi Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 4, R. Koleksi Jurnal
  • Ketersediaan
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No. Panggil No. Barkod Ketersediaan
610 AAIR 9:6 (2017) 03-18-519725561 TERSEDIA
Ulasan:
Tidak ada ulasan pada koleksi ini: 20471961
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