Artikel Jurnal :: Kembali

Artikel Jurnal :: Kembali

Chronic spontaneous urticaria: pathogenesis and treatment considerations / Allen P. Kaplan

Allen P. Kaplan; (The Korean Academy of Asthma, Allergy and Clinical Immunology, 2017)

 Abstrak

ABSTRACT
The treatment of chronic spontaneous urticaria begins with antihistamines; however, the dose required typically exceeds that recommended for allergic rhinitis. Second-generation, relatively non-sedating H₁receptor blockers are typically employed up to 4 times a day. Firstgeneration antihistamines, such as hydroxyzine or diphenhydramine (Atarax or Benadryl), were employed similarly in the past. Should high dose antihistamines fail to control symptoms (at least 50%), omalizumab at 300 mg/month is the next step. This is effective in 70% of antihistamine refractory patients. H₂receptor blockers and leukotriene antagonists are no longer recommended; they add little and the literature does not support significant efficacy. For those patients who are unresponsive to both antihistamines and omalizumab, cyclosporine is recommended next. This is similarly effective in 65%-70% of patients; however, care is needed regarding possible side effects on blood pressure and renal function. Corticosteroids should not be employed chronically due to cumulative toxicity that is dose and time dependent. Brief courses of steroid e.g., 3 to 10 days can be employed for severe exacerbations, but should be an infrequent occurrence. Finally, other agents, such as dapsone or sulfasalazine, can be tried for those patients unresponsive to antihistamines, omalizumab, and cyclosporine.

 Metadata

Jenis Koleksi : Artikel Jurnal
No. Panggil : 610 AAIR 9:6 (2017)
Entri utama-Nama orang :
Subjek :
Penerbitan : Suwon: The Korean Academy of Asthma, Allergy and Clinical Immunology, 2017
Sumber Pengatalogan : LibUI eng rda
ISSN : 20927355
Majalah/Jurnal : Allergy, Asthma & Immunology Research
Volume : Vol. 9, No. 6, November 2017: 477-482
Tipe Konten : text
Tipe Media : unmediated
Tipe Carrier : volume
Akses Elektronik :
Institusi Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 4, R. Koleksi Jurnal
  • Ketersediaan
  • Ulasan
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No. Panggil No. Barkod Ketersediaan
610 AAIR 9:6 (2017) 03-18-291917496 TERSEDIA
Ulasan:
Tidak ada ulasan pada koleksi ini: 20471962
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