Artikel Jurnal :: Kembali

Artikel Jurnal :: Kembali

Low-risk donor lungs optimize the post lung transplant outcome for high lung allocation score patients

Takeshi Kurosaki, Kentaroh Miyoshi, Shinji Otani, Kentaro Imanishi, Seiichiro Sugimoto, Masaomi Yamane, Motomu Kobayashi, Shinichi Toyooka, Takahiro Oto (Springer, 2018)

 Abstrak

ABSTRACT
Purpose
The lung allocation score (LAS) has been generally recognized as a contributor to the overall survival in lung transplant candidates. However, donor-related risks have never been taken into consideration in previous research that validated the LAS. This study aimed to determine whether or not the role of the LAS as a predictor of the posttransplant outcome is influenced by the quality of the donor lungs.
Methods
We retrospectively reviewed 108 patients who underwent lung transplantation at Okayama University Hospital since 1998. The cohort was divided into two groups based on the lung donor score (DS; ≤ 4/> 4). Correlations between the LAS and posttransplant outcomes were investigated in both groups.
Results
In the high-DS group, an elevated LAS was strongly associated with posttransplant PaO2/FiO2 (p = 0.018). However, in the low-DS group, no correlation was found between them. There was no significant difference in the long-term survival according to the LAS in the low-DS group. The LAS effectively predicted the posttransplant outcome only when lungs with DS > 4 were transplanted; the LAS was not reliable if high-quality lungs were transplanted.
Conclusion
Lung transplantation can be feasible and provides a survival benefit even for high-LAS patients if lungs from a low-risk donor are transplanted.

 Metadata

Jenis Koleksi : Artikel Jurnal
No. Panggil : 617 SUT 48:10 (2018)
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Penerbitan : Tokyo: Springer, 2018
Sumber Pengatalogan : LibUI eng rda
ISSN : 09411291
Majalah/Jurnal : Surgery Today Official Journal of The Japan Surgical Society
Volume : Vol. 48 No. 10, October 2018: Hal. 928-935
Tipe Konten : text
Tipe Media : unmediated (rda media)
Tipe Carrier : volume
Akses Elektronik :
Institusi Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI, Lantai 4, R. Koleksi Jurnal
  • Ketersediaan
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No. Panggil No. Barkod Ketersediaan
617 SUT 48:10 (2018) 03-19-825922058 TERSEDIA
Ulasan:
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