Prevalensi HIV/AIDS di dunia semakin meningkat. Lelaki seks lelaki (LSL ) merupakan populasi yang paling mudah terkena HIV/AIDS. Penularan terjadi karena rendahnya penggunaan kondom. Penelitian ini bertujua untuk mengidentifkasi hubungan self-efficacy kondom dan spiritualitasterhadap perilaku penggunaan kondom. Penelitian ini menggunakan desain cross sectional dengan teknik consecutive sampling pada 250 ODHA LSL.Hasil penelitian menunjukkan bawah ada hubungan yang signfikan antara self-efficacy kondom dengan perilaku penggunaan kondom p-value <0.05 (OR = 11.298; 95% CI: 4.35-20.1 ) dan spiritualitas terhadap perilaku penggunaan kondom p-value< 0.05 (OR = 3.405; 95% CI : 0.85-3.21). Pada analisis multivariat regresi logistik berganda, self-efficacy kondom merupakan faktor yang paling mempengaruhi perilaku penggunaan kondom. Sehingga untuk meningkatkan konsistensi penggunaan kondom perawat perlu mengedepankan intervensi misalnya kegiatan konseling yang berfokus pada peningkatan keyakinan diri (self-efficacy).

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The prevalence of HIV/AIDS in the world is increasing. Men who have sex with men (MSM) is the populations most vulnerable to HIV/AIDS. Transmission occurs because of the low use of condoms. This study aimed to identify the relationship of condom self-efficacy and spirituality to condom use behaviour. This study used a cross-sectional design with consecutive sampling techniques in 250 ODHA MSM. The results show that there was a significant relationship between condom self-efficacy and condom use behavior p value <0.05 (OR = 11.298; 95% CI: 4.35-20.1 ) and spirituality towards condom use behavior p-value< 0.05 (OR = 3.405; 95% CI : 0.85-3.21). In multivariate analysis of multiple logistic regression, condom self-efficacy is the factor that most influences condom use behaviour. So to improve the consistency of condom use nurses need to prioritize interventions such as counselling activities that focus on increasing self-confidence (selfefficacy).