Coronavirus Disease 2019 telah menimbulkan pandemi dengan penyebaran dan peningkatan jumlah kasus COVID-19 terjadi secara cepat pada berbagai wilayah di seluruh dunia termasuk Indonesia. Kecamatan Purwokerto Selatan merupakan wilayah dengan kasus COVID-19 paling tinggi di Kabupaten Banyumas terhitung hingga 31 Maret 2021 sebanyak 805 kasus, kematian mencapai 28 orang dan angka CFR sebesar 3,47%. Guna mendukung upaya pencegahan penyebaran COVID-19, diperlukan adanya gambaran wilayah rawan akan peningkatan kasus dan kematian COVID-19. Namun, gambaran zona kerawanan COVID-19 berdasarkan faktor risiko belum dilakukan, sehingga acuan wilayah dalam pencegahan wilayah yang rawan COVID-19 belum dapat dilakukan. Penelitian bertujuan untuk mengetahui korelasi, hubungan spasial faktor risiko dengan kejadian COVID-19 dan menentukan zona kerawanan COVID-19 berdasarkan faktor risiko melalui pendekatan SIG. Metode penelitian yang digunakan deskriptif kuantitatif dengan pendekatan studi ekologi. Populasi dan sampel dari penelitian yaitu kasus COVID-19 yang tercatat di Kecamatan Purwokerto Selatan pada tahun 2020. Hasil penelitian menunjukkan faktor risiko kemiskinan (p-value = 0,034 r = 0,791) mempengaruhi jumlah kasus COVID-19 secara signifikan dan memiliki hubungan yang sangat kuat. Jumlah KK pengguna sanitasi umum (p-value = 0,094; r = 0,679) dan cakupan rumah tangga ber-PHBS (p-value = 0,251; r = 0,502) tidak mempengaruhi secara signifikan, namun ada hubungan yang kuat terhadap jumlah kasus COVID-19, dan kepadatan penduduk tidak berhubungan secara signifikan (p-value = 0,658). Secara spasial ada hubungan jumlah kasus COVID-19 dengan kemiskinan dan KK pengguna sanitasi umum. Zona kerawanan tinggi peningkatan COVID-19 di Kecamatan Purwokerto Selatan yaitu kelurahan Teluk dan Karangklesem. Diperlukan upaya pencegahan dan intervensi difokuskan pada wilayah dengan zona kerawanan tinggi dan pada wilayah penduduk dengan tingkat kemiskinan yang tinggi.

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The Coronavirus Disease 2019 has caused pandemic with the spread and increase in the number of COVID-19 cases occurring rapidly in various regions throughout the world, including Indonesia. Purwokerto Selatan Sub-District is the area with the highest COVID-19 cases in Banyumas District as of March 31, 2021 as many as 805 cases, 28 deaths and a CFR rate of 3.47%. In order to support efforts to prevent the spread of COVID-19, it is necessary to have an overview of areas prone to an increase in COVID-19 cases and deaths. However, the description of the COVID-19 vulnerability zone based on risk factors has not been carried out, so regional references in preventing COVID-19-prone areas cannot be carried out.

This study aims to determine the correlation, spatial relationship of risk factors with the incidence of COVID-19 and determine the COVID-19 vulnerability zone based on risk factors through a GIS approach. The research method used is descriptive quantitative with an ecological study approach. The population and sample of the study were COVID-19 cases recorded in Purwokerto Selatan Sub-District in 2020. The results showed that poverty (p-value = 0.034 r = 0.791) significantly affected the number of COVID-19 cases and had a very strong relationship. The number of households using public sanitation (p-value = 0.094; r = 0.679) and the coverage of PHBS households (p-value = 0.251; r = 0.502) did not significantly affect, but there was a strong relationship with the number of COVID-19 cases, and population density were not significantly related (p-value = 0.658). Spatially there is a relationship between the number of COVID-19 cases and poverty and households using public sanitation. The high-risk zone for the increase in COVID-19 in Purwokerto Selatan Sub-District, namely Teluk and Karangklesem village. The need for prevention and intervention efforts are focused on areas with high vulnerability zones and areas with high poverty levels.