Latar Belakang: Skabies merupakan penyakit menular yang diakibatkan oleh tungau Sarcoptes scabiei varietas homonis. Penyakit skabies sering terjadi pada lingkungan yang berpenghuni padat seperti pondok pesantren. Kejadian skabies selain mengganggu kesehatan santri namun akan berdampak kepada performa santri untuk menjalankan kegiatan sehari-hari.Tujuan: Mengetahui hubungan faktor lingkungan dan personal hygiene dengan kejadian skabies pada santri di pesantren X di Kota Bogor pada Tahun 2022.Metode: Studi cross sectional yang dilakukan pada 1 pesantren di Kota Bogor. Hasil: Sebanyak 65 orang (77,4%) mengalami skabies, dan 19 orang (22,6%) tidak mengalami skabies. Tidak ada hubungan yang signifikan antara faktor lingkungan yaitu suhu dan kelembaban dengan kejadian. Sedangkan faktor personal hygiene seperti kebersihan tangan, kebersihan kuku, kebersihan kulit, kebersihan handuk dan kebersihan pakaian memiliki hubungan yang signifikan dengan kejadian skabies.

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Background: Scabies is an infectious disease caused by the mite Sarcoptes scabiei homonis variety. Scabies disease often occurs in densely inhabited environments such as Islamic boarding schools. The incidence of scabies in addition to disturbing the health of students but will have an impact on the performance of students to carry out daily activities.

Objective: To determine the relationship between environmental factors and personal hygiene with the incidence of scabies in students at Islamic boarding school X in Bogor City in 2022.

Method: Cross sectional study conducted at 1 Islamic boarding school in Bogor City.

Results: As many as 65 people (77.4%) had scabies, and 19 people (22.6%) did not experience scabies. There is no significant relationship between environmental factors, namely temperature and humidity with the incidence. Meanwhile, personal hygiene factors such as hand hygiene, nail hygiene, skin hygiene, towel hygiene and clothing hygiene have a significant relationship with the incidence of scabies.