Bank BUMN sebagai mitra strategis pemerintah berperan dalam mendukung pelaksanaan pembangunan nasional dalam rangka pertumbuhan ekonomi, peningkatan kekayaan negara, pemerataan pembangunan, dan stabilitas nasional ke arah peningkatan taraf hidup masyarakat luas. Oleh karena itu, Bank BUMN diperlukan untuk memiliki kinerja yang baik dalam menjalankan kegiatan usahanya. Indikator yang mampu merepresentasikan dengan baik kinerja Bank BUMN adalah profitabilitas. Penelitian ini bertujuan untuk menganalisis determinan profitabilitas dengan menguji pengaruh Firm Size, Liquidity, Solvency, Financial Leverage, dan Capital Adequacy terhadap ROA, ROE, danROS. Penelitian ini adalah penelitian dengan pendekatan kuantitatif, menggunakan teknik penarikan sampel purposive sampling, dan menggunakan model statistik regresi berganda data panel. Data yang digunakan dalam penelitian ini adalah laporan keuangan dan laporan tahunan Bank Mandiri, Bank BNI, Bank BRI, danBank BTN periode 2016-2019. Hasil penelitian menunjukkan bahwa terdapat pengaruh positif antara Firm Size terhadap ROAdan ROS namun negatif terhadap ROE. Liquidity berpengaruh positif terhadap ROEdan ROS namun negatif terhadap ROA. Solvency berpengaruh negatif terhadap ROA, ROE, dan ROS. Financial Leverage berpengaruh positif terhadap ROAnamun negatif terhadap ROEdan ROS. Capital Adequacy berpengaruh positif terhadap ROAdan ROEnamun negatif terhadap ROS.

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As strategic partners of the government, state-owned banks play a role in supporting the implementation of national development in the context of economic growth, increasing the country’s wealth, equitable development, and national stability towards improving living standards. Therefore, state-owned banks must persist to have good performance in all its business activities. An indicator that can represent well the performance of state-owned banks is profitability. This research aims to analyze the determinants of profitability. Those determinants include Firm Size, Liquidity, Solvency, Financial Leverage, and Capital Adequacy while the profitability is evaluated by three different ratios which is ROA, ROE, and ROS. This research is using a quantitative research with a purposive sampling technique and used a multiple regression statistical model of panel data. The data used in this research are the financial statements and annual reports of Bank Mandiri, Bank BNI, Bank BRI, and Bank BTN for the 2016-2019 period. The research results showed that Firm Size has a positive impact on both ROA and ROS but a negative one on ROE. Liquidity impacts positively on ROE and ROS but negatively on ROA. Solvency impacts negatively on ROA, ROE, and ROS. Financial Leverage has a positive impact on ROA but it has the opposite effect on ROE and ROS. Capital Adequacy has a positive impact on both ROA and ROE but negative on ROS.