Artikel Jurnal :: Kembali

Artikel Jurnal :: Kembali

Specific subjective symptoms for gastroesophageal reflux disease in ulcer like dyspepsia

by Irsan Hasan ... [and others] ([Publisher not identified] , 2004)

 Abstrak

Background: The determination of branched chain amino acids (BCAA) to tyrosine ratio (BTR) was available in making differentiation of chronic hepatitis from liver cirrhosis, because there was a strong association between BTR and staging (fibrosis) scores. Branched chain ammo acids to tyrosine ratio have a correlation with Fischer ratio and the examination is easier because it can be done by enzymatic assay.
Materials and Methods: To evaluate the correlation between BTR and Child-Pugh score, we examined the amino gram of 52 liver cirrhosis patients consisted of 26 Child-Pugh A, 19 Child-Pugh B, and 7 Child-Pugh C. The examination of amino gram was done by High Pressure Liquid Chromatograph (HPLC) analyzer. Branched chain amino acids to tyrosine ratio were compared to Child-Pugh score, albumin, ammonia level, number connection test to Fischer ratio.
Results: Significant differences in BTR among Child-Pugh A, B, C were observed (Child-Pugh A 7.75 ± 1.2; Child Pugh B 6.0 ± 1.23 and Child Pugh C 4.38 + 3.14 (p = 0.000)). Branched chain amino acids to tyrosine ratio had a weak correlation with albumin fr - 0.292; p = 0.036), ammonia level (r = 0.376; p = 0.006) and strong correlation with Fischer ratio (r = 0.818; p = 0.000). There was no significant correlation between BTR and number connection test.
Conclusion: These results showed that the determination of the molar ratio of branched chain amino acids to tyrosine well reflected the severity of liver cirrhosis and it can be used as a substitute of Fischer ratio.

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 Metadata

Jenis Koleksi : Artikel Jurnal
No. Panggil : IJGH-5-1-April2004-7
Entri utama-Nama orang :
Penerbitan : [Place of publication not identified]: [Publisher not identified], 2004
Sumber Pengatalogan :
ISSN :
Majalah/Jurnal : The Indonesia Journal of Gastroenterology Hepatology and Digestive Endoscopy
Volume : Vol. 5 (1) April 2004: 7-14
Tipe Konten :
Tipe Media :
Tipe Carrier :
Akses Elektronik :
Institusi Pemilik : Universitas Indonesia
Lokasi :
  • Ketersediaan
  • Ulasan
  • Sampul
No. Panggil No. Barkod Ketersediaan
IJGH-5-1-April2004-7 03-20-988204223 TERSEDIA
Ulasan:
Tidak ada ulasan pada koleksi ini: 90096
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