This research is intended to identify the description of the performance and factors that effect the performance of the drugs personnel in managing report of drug request utilization (LPLPO). The research method use cross-sectional design. The research location are all community health centers that available in distrcit of Padang Pariaman and district of Agam with respondents of 46 drug personnel of community health centers. Data collection is done by filling-up questionaire, and continued with monthly checking of documents of report of drug request utilization (LPLO).Results of the research indicate that performance of the drug personnel of the community health is 67,4%. The results of research regarding the description of performance level of drug personnel of the community health centers is viewed in terms of internal and external factors. Regarding significant variables after chi-square test, the internal factor related with the performance of drug personnel is the work tenure and level of education, while knowledge does not show significant relationship. Within the external factors, only training is significantly related to the performance. While othe factors, i.e., remuneration, support of coworkers, supervision, and work load do not have significant relationship. From the multivariate analysis the most dominant variable is education. The suggestion from the result of this reseacrh is that it is ecxpected that the province needs to recommend personnel recruitment to manage the drug at the community health centers with formal education of assitant pharmacist. the suggestion for districts is that refreshing training for drug personnel needs to be done periodic meetings need to be done.