Penelitian ini bertujuan untuk menganalisis pengaruh dari modal manusia, modal sosial, berbagi pengetahuan, kreativitas karyawan, dan kebermaknaan kerja terhadap perilaku kerja inovatif karyawan di perusahaan farmasi di Indonesia. Pengumpulan data dilakukan menggunakan kuesioner online dengan jumlah responden sebesar 286 responden di perusahaan farmasi di Indonesia dan data dianalisis menggunakan metode structural equation modeling (SEM) dengan software SPSS Amos versi 24. Hasil penelitian menyatakan bahwa modal manusia memiliki pengaruh positif dan signifikan terhadap modal sosial, yang selanjutnya memiliki pengaruh positif dan signifikan terhadap berbagi pengetahuan, dan selanjutnya memiliki pengaruh positif dan signifikan terhadap kreativitas karyawan. Seperti yang diharapkan, kreativitas karyawan memiliki pengaruh positif dan signifikan terhadap perilaku kerja inovatif. Hubungan antara modal sosial dan kreativitas karyawan dimediasi oleh berbagi pengetahuan, dan hubungan antara berbagi pengetahuan dan perilaku kerja inovatif dimediasi oleh kreativitas karyawan. Sebagai variabel moderasi, kebermaknaan kerja memoderasi hubungan antara modal sosial dan berbagi pengetahuan. Modal manusia tidak menunjukkan pengaruh langsung yang signifikan terhadap berbagi pengetahuan, namun, modal sosial memediasi hubungan antara modal manusia dan berbagi pengetahuan. Penelitian ini memberikan wawasan bagi praktisi di perusahaan farmasi di Indonesia tentang bagaimana meningkatkan perilaku kerja inovatif karyawannya melalui pengembangan modal manusia, modal sosial, berbagi pengetahuan, dan kebermaknaan kerja karyawannya, untuk memperkuat lingkungan kreatif dan inovatif bagi karyawannya.

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This study aims to analyze the influence of human capital, social capital, knowledge sharing, employee creativity, and work meaningfulness on employee innovative work behavior in pharmaceutical companies in Indonesia. Data were collected using an online questionnaire with a total of 286 respondents in pharmaceutical companies in Indonesia and data were analyzed using the structural equation modeling (SEM) method with SPSS Amos software version 24. The results stated that human capital has a positive and significant effect on social capital, which in turn has a positive and significant effect on knowledge sharing, and subsequently has a positive and significant effect on employee creativity. As expected, employee creativity has a positive and significant effect on innovative work behavior. The relationship between social capital and employee creativity is mediated by knowledge sharing, and the relationship between knowledge sharing and innovative work behavior is mediated by employee creativity. As a moderating variable, work meaningfulness moderates the relationship between social capital and knowledge sharing. Human capital showed no significant direct effect on knowledge sharing, however, social capital mediates the relationship between human capital and knowledge sharing. This study provides insights for practitioners in pharmaceutical companies in Indonesia on how to improve the innovative work behavior of their employees through the development of human capital, social capital, knowledge sharing, and work meaningfulness of their employees, to strengthen the creative and innovative environment for their employees.