Pendahuluan: pandemic Covid-19 yang berlangsung saat ini masih menjadi masalah global termasuk ODHA. Dimana ODHA merupakan seorang individu dengan HIV AIDS yang memiliki daya tahan tubuh yang lemah atau imunodefisiensi sehingga rentan sekali terhadap paparan penyakit yang disebabkan oleh virus Covid-19. Tujuan dari penelitian ini adalah untuk mengetahui sejauh mana pengaruh hubungan persepsi kerentanan dan sikap ODHA terhadap perilaku pencegahan Covid-19. Metode: menggunakan desai penelitian cross sectional, dengan jumlah sampel sebanyak 106 orang responden di Yayasan lekas bogor. Teknik sampling yang digunakan adalah convenience sampling. Hasil penelitian menunjukan terdapat hubungan yang signifikan pada persepsi kerentanan dengan perilaku upya pencegahan covid-19 (p<0,03) san sikap ODHA terhadap perlaku upaya pencegahan covid-19 (p<0,01). Kesimpulan: terdapat hubungan yang signifikan pada persepsi kerentanan dan sikap ODHA dengan perilaku upaya pencegahan covid-19. Saran: dilakukannya edukasi terhadap respon yang negatif mengenai persepsi kerentanan dan sikap ODHA terhadap perilaku upaya pencegahan covid-19 dan memfasilitasi permasalahan yang di hadapi ODHA.

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Introduction: the ongoing Covid-19 pandemic is still a global problem, including PLHIV. Where PLWHA are individuals with HIV AIDS who have weak immune systems or are immunodeficient so they are very vulnerable to exposure to diseases caused by the Covid-19 virus. The purpose of this study was to determine the influence of the relationship between perceptions of vulnerability and attitudes of PLHIV on Covid-19 prevention behavior. Methods: using a cross-sectional research design, with a total sample of 106 respondents at the Lekas ​​Bogor Foundation. The sampling technique used is convenience sampling. The results showed that there was a significant relationship between perceptions of vulnerability and the behavior of Covid-19 prevention efforts (p<0.03) and the attitude of PLWHA towards the treatment of Covid-19 prevention efforts (p<0.01). Conclusion: there is a significant relationship between perceptions of vulnerability and attitudes of PLHIV with the behavior of Covid-19 prevention efforts. Suggestion: conduct education on negative responses regarding perceptions of vulnerability and attitudes of PLWHA towards the behavior of efforts to prevent Covid-19 and facilitate the problems faced by PLWHA.