This volume presents the Proceedings of the Sixth International Conference on Green and Human Information Technology (ICGHIT), held in Chiang Mai, Thailand, Jan 31-Feb 2, 2018.ICGHIT is the unique global conference for researchers, industry professionals, and academics interested in the latest development of green and human information technology. Its broad scope ranges from electronics to communications, computers, multimedia and signal processing, control and intelligent systems, IC and convergence technologies, which are related to green and human issues such as energy saving and human welfare. Specially in this volume, ICGHIT covers state-of-the-art technologies for the 4th industrial revolution, for example, cyber security, big data and cloud service, smart medical system, machine learning and its applications.