Secara global, insiden TB dunia pada tahun 2015 sebesar 10,4 juta kasus.Indonesia berada di urutan kedua dari total kasus diseluruh dunia sebesar 10%,setelah India. Prevalensi TB berdasarkan provinsi yang tertinggi adalah JawaBarat (0,7%). Padatnya tingkat hunian di pesantren dapat menimbulkan kondisirentan sehingga dianggap memicu banyaknya kasus TB. Pengendalian TBberbasis masyarakat merupakan salah satu upaya promosi kesehatan dalampenanggulangan TB. Penelitian ini bertujuan mengetahui dampak pemberdayaansantri kader TB terhadap perilaku pencegahan TB di pondok pesantren Garut JawaBarat. Metode penelitian kuantitatif dengan desain kuasi eksperimen pada 230santri sebagai sampel pada masing-masing kelompok intervensi dan kontrol.Pengumpulan data dilakukan sebanyak 2 kali yaitu pengumpulan data awal,setelah itu dilakukan intervensi berupa pelatihan pada 30 santri yang terpilihsebagai kader TB dengan melakukan penyuluhan dan kunjungan kamar 2 bulankemudian dilakukan pengumpulan data akhir. Analisis yang digunakan adalah ujiwilcoxon, mann-whitney dan uji regresi logistic ganda model faktor resiko. Hasilpenelitian membuktikan santri yang mendapat intervensi berpeluang memilikiperilaku pencegahan baik hampir 3 kali (OR=2,90; 95%CI= 1,9-4,4)dibandingkan dengan santri yang tidak mendapatkan intervensi setelah dikontroljenis kelamin santri.

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Globally, the incidence of tb in 2015 amounted to 10.4 million cases. tb ranks in

the 2nd place of the total cases all over Indonesia by 10% after India. The highest

prevalence of TB by province is western Java (0.7%,). Tb incidence did not occur

only in the general population, but also arise in certain community such as islamic

boarding schools. The density of occupancy in Islamic boarding school can cause

vulnerable condition causing many cases of tb. Community-based TB control is

one of health promotion efforts in TB prevention. This study aims to determine

the impact of Empowerment of Tuberculosis (TB) Against Student Cadres

Behavior in TB Prevention at Islamic boarding school, Garut, West Java.

Quantitative research method with quasi experimental design on 230 students as

sample in each intervention and control group. Data collection was done 2 times,

that is initial data collection, after that do intervention in the form of training at 30

students selected as TB cadre by doing counseling and visit room 2 month later to

do final data collecting. The analysis used was wilcoxon test, mann-whitney and

multiple logistic regression test of risk factor model. The result of the research

shows that students who have intervention have a good prevention behavior

almost 3 times (OR = 2,90; 95% CI = 1,9-4,4) compared with students who do not

get intervention after separation of gender.