Tuberkulosis (TB) merupakan salah satu jenis penyakit menular yang disebabkan oleh suatu bakteri, yakni Mycobacterium tuberculosis. Merujuk pada World Health Organization (WHO), TB berada pada urutan kedua infeksi yang paling mematikan setelah COVID-19 dan penyebab utama ke-13 kematian di seluruh dunia. Hingga saat ini, kepatuhan pasien terhadap pengobatan TB masih menjadi tantangan tersendiri dalam meningkatkan keberhasilan terapi. Penulisan ini bertujuan untuk memperoleh gambaran tingkat kepatuhan penggunaan obat Pasien Tuberkulosis Resistan Obat di Puskesmas Kecamatan Cengkareng Periode Maret 2022 hingga April 2023. Metode pelaksanaan dilakukan dengan mengolah data terkait pasien yang menerima pengobatan TB RO di Puskesmas Kecamatan Cengkareng Periode Maret 2022 hingga April 2023. Berdasarkan penelitian, sebanyak 70% termasuk dalam kategori patuh dikarenakan masih menjalani pengobatan secara aktif, 17% mengalami ketidakberhasilan terapi (7% meninggal dunia, 7% gagal pengobatan, dan 3% putus obat), 3% sembuh, 3% dirujuk ke fasilitas kesehatan lain, dan 3% masih menunggu hasil kultur bakteri.

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Tuberculosis (TB) is a type of infectious disease caused by a bacteria, namely Mycobacterium tuberculosis. Referring to the World Health Organization (WHO), TB is the second most deadly infection after COVID-19 and the 13th leading cause of death worldwide. Until now, patient compliance with TB treatment is still a challenge in increasing the success of therapy. This writing aims to obtain an overview of the level of compliance with drug use in Drug-Resistant Tuberculosis Patients at Puskesmas Cengkareng for the period March 2022 to April 2023. The implementation method is carried out by processing data related to patients who received RO TB treatment at Puskesmas Cengkareng for the period March 2022 to April 2023. Based on research, as many as 70% were included in the compliant category because they were still undergoing active treatment, 17% experienced unsuccessful therapy (7% died, 7% failed treatment, and 3% dropped out of medication), 3% recovered, 3% were referred to other health facilities , and 3% are still waiting for bacterial culture results.