Penelitian bertujuan menganalisis determinan kinerja pelaksana manajemen sistem informasi kesehatan di lingkungan Dinas Kesehatan Kabupaten Bondowoso. Merupakan penelitian kuantitatif dengan pendekatan sistem menggunakan metode cross sectional. Kuesioner online dengan google form disebarkan melalui whatsapp group terhadap sampel penelitian yaitu seluruh (111 responden) pelaksana manajemen sistem informasi kesehatan di 25 puskesmas. Hasil menunjukkan responden berkinerja baik 55,0%. Menggunakan uji Chi-Square faktor input yang berpengaruh signifikan (p<0,05) terhadap output berupa kinerja adalah usia, pendidikan terakhir, keterampilan, pengetahuan, dan sarana prasarana.

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This study aims to analyze the performance determinants of human resources of health information system management in primary health care centre in the Bondowoso Departement of Health district.. This is a quantitative research with a systems approach using a cross sectional method. An online questionnaire using google form was distributed via whatsapp group to the sample of this study are all of human resources of health information system management in primary health care centre (111 respondents). The results showed that the respondents performed well 55.0%. Using the Chi-Square test, the input factors that have a significant effect (p <0.05) on the output in the form of performance are age, last education, skills, knowledge, and infrastructure.