Acute Lymphoblastic Leukemia (ALL) merupakan kasus kanker yang paling sering dijumpai pada anak di Indonesia. Upaya yang dapat dilakukan untuk mengatasi penyakit ini ialah dengan kemoterapi. Patologis penyakit ALL dan efek samping pengobatannya dapat menyebabkan berbagai masalah keperawatan salah satunya adalah fatigue atau keletihan. Model konservasi Levine menjadi dasar intervensi keperawatan yang diberikan untuk mengatasi masalah keperawatan fatigue atau keletihan. Penerapan model konservasi Levine bertujuan agar seorang individu mampu beradaptasi dan tetap mempertahankan kualitas hidupnya. Model konservasi Levine tidak hanya berfokus kepada konservasi energi melainkan secara holistik. Terdapat empat prinsip diantaranya konservasi energi, integritas struktural, integritas personal, serta integritas sosial. Berdasarkan hasil evaluasi yang dilakukan, terdapat penurunan tingkat keletihan dengan kriteria peningkatan nafsu makan, kulit tidak pucat, kenaikan hemoglobin, tanda-tanda vital (TTV) stabil, serta peningkatan kemampuan melakukan aktivitas secara mandiri yakni makan dan minum.

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Acute Lymphoblastic Leukemia (ALL) is the most common cancer case in children in Indonesia. Treatment that can be done to overcome this disease is chemotherapy. The pathology of ALL and the side effects of its treatment can cause various nursing problems, one of which is fatigue. Levine's conservation model is the basis for nursing interventions that are given to overcome the nursing problem: fatigue. The application of Levine's conservation model aims for an individual to be able to adapt and still maintain his quality of life. Levine's conservation model does not only focus on energy conservation but holistically. There are four principles including energy conservation, structural integrity, personal integrity, and social integrity. Based on the results of the evaluation carried out, there was a decrease in the level of fatigue with the criteria of increased appetite, not pale skin, increased hemoglobin, stable vital sign, and increased ability to do activities independently, such as eating and drinking.